3-(carbamoylamino)-2-methyl-propanoic acid
名称
[ CAS 号 ]:
2905-86-4
[ 英文名 ]:
3-(carbamoylamino)-2-methyl-propanoic acid
[英文别名 ]:
- 3-carbamoylamino-2-methylpropanoic acid
- 3-Ureido-isobuttersaeure
- 3-ureido-2-methyl-propanoic acid
- 3-Ureidoisobutyrate
- 3-(carbamoylamino)-2-methylpropanoic acid
- DL-3-Ureidoisobutyric acid
物理化学性质
[ 密度 ]:
1.263g/cm3
[ 沸点 ]:
317.5ºC at 760mmHg
[ 分子式 ]:
C5H10N2O3
[ 分子量 ]:
146.14400
[ 闪点 ]:
145.8ºC
[ 精确质量 ]:
146.06900
[ PSA ]:
93.41000
[ LogP ]:
0.28010
[ 蒸汽压 ]:
8.12E-05mmHg at 25°C
[ 折射率 ]:
1.497
MSDS
安全信息
[ 符号 ]:
GHS05
[ 信号词 ]:
Danger
[ 危害声明 ]:
H318
[ 警示性声明 ]:
P280-P305 + P351 + P338 + P310
[ 危险品运输编码 ]:
NONH for all modes of transport
[ 海关编码 ]:
2924199090
合成路线
上下游产品
上游产品
下游产品
海关
[ 海关编码 ]: 2924199090
[ 中文概述 ]:
2924199090. 其他无环酰胺(包括无环氨基甲酸酯)(包括其衍生物及盐). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 包装
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
文献
Hum. Mol. Genet. 13(22) , 2793-801, (2004)
beta-Ureidopropionase deficiency is an inborn error of the pyrimidine degradation pathway, affecting the cleavage of N-carbamyl-beta-alanine and N-carbamyl-beta-aminoisobutyric acid. In this study, we...
Sensitive method for the quantification of urinary pyrimidine metabolites in healthy adults by gas chromatography-tandem mass spectrometry.J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 791(1-2) , 371-80, (2003)
Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil. To assess whether urinary levels of pyrimidines and their m...
Screening and diagnosis of beta-ureidopropionase deficiency by gas chromatographic/mass spectrometric analysis of urine.J. Mass Spectrom. 37(9) , 954-62, (2002)
Dihydropyrimidine dehydrogenase (DHPDase), dihydropyrimidinase (DHPase) and beta-ureidopropionase (betaUPase) are the enzymes that catalyze the first, second, and third steps of the degradation of pyr...
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