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2,3,5-三苯基氯化四氮唑

2,3,5-三苯基氯化四氮唑用途

Tetrazolium Red(2,3,5-Triphenyltetrazolium chloride; TPTZ)用于观察脱氢酶的活性,遇氢后有无色变为红色。

2,3,5-三苯基氯化四氮唑名称

[ CAS 号 ]:
298-96-4

[ 中文名 ]:
2,3,5-三苯基氯化四氮唑

[ 英文名 ]:
2,3,5-Triphenyltetrazolium chloride

[中文别名 ]:

[英文别名 ]:

2,3,5-triphenyl tetrazolium chloride
TETRAZOLE RED
TTC
Red tetrazolium
triphenyltetrazolium chloride
urocheck
TPTZ,TTZ,Tetrazolium Red
TTL
EINECS 206-071-6
vitastain

2,3,5-三苯基氯化四氮唑生物活性

[ 描述 ]:

Tetrazolium Red(2,3,5-Triphenyltetrazolium chloride; TPTZ)用于观察脱氢酶的活性,遇氢后有无色变为红色。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

生化试剂

研究领域 >> 其他

[相关活性小分子]

2,3,5-三苯基氯化四氮唑物理化学性质

[ 沸点 ]:
>360

[ 熔点 ]:
250 °C(lit.)

[ 分子式 ]:
C₁₉H₁₅ClN₄

[ 分子量 ]:
334.802

[ 闪点 ]:
91.7ºC

[ 精确质量 ]:
334.098511

[ PSA ]:
34.59000

[ LogP ]:
0.21500

[ 外观性状 ]:
白色至黄色带有一种淡黄褐色的粉末

[ 蒸汽压 ]:
0.0615mmHg at 25°C

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Light sensitive. Protect from moisture. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
H2O: may be clear to slightly hazy

2,3,5-三苯基氯化四氮唑MSDS

详细MSDS(安全技术说明书)

2,3,5-三苯基氯化四氮唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XF8100000

CHEMICAL NAME :: 2H-Tetrazolium, 2,3,5-triphenyl-, chloride

CAS REGISTRY NUMBER :: 298-96-4

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C19-H15-N4.Cl

MOLECULAR WEIGHT :: 334.83

WISWESSER LINE NOTATION :: T5NNKNJ BR& CR& ER &G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5600 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00925 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83592 No. of Facilities: 11 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 32 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83592 No. of Facilities: 32 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1665 (estimated) No. of Female Employees: 1207 (estimated)

2,3,5-三苯基氯化四氮唑安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
XF8100000

[ 海关编码 ]:
2933990090

2,3,5-三苯基氯化四氮唑合成路线

详细合成路线

2,3,5-三苯基氯化四氮唑上下游产品

2,3,5-三苯基氯化四氮唑上游产品

2,3,5-三苯基氯化四氮唑下游产品

2,3,5-三苯基氯化四氮唑制备

1.合成苯腙：苯肼溶于95%乙醇中，加入苯甲醛水浴回流1h即得苯腙。
2.偶合：将苯腙溶于吡啶中，与苯胺重氮盐偶合。
3.合成2- 3-5- 三苯基氯化四氮唑：将上述偶合物溶于甲醇中加入亚硝酸异戊酯，然后慢慢加入通过盐酸气的甲醇溶液，加完放置3～4h，再通盐酸气20min狀，水浴加热片刻，加入蒸馏水蒸出甲醇后，脱色过滤干燥得粗品（此步需在暗处操作）。
4精制：粗品用水溶解加热，脱色，过滤，然后减压浓缩近干，滤出结晶，用少量丙酮冲洗即为成品。

2,3,5-三苯基氯化四氮唑海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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