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2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐用途

壬酸二乙胺(DEA壬酸二乙酯,二乙基铵盐)是一氧化氮供体。壬酸二乙胺是一种有效的抗菌剂,可以抑制大肠杆菌的生长。壬酸二乙胺还可以加强供体大鼠心脏的保存[1][2]。

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐名称

[ CAS 号 ]:
372965-00-9

[ 中文名 ]:
2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐

[ 英文名 ]:
Diethylamine NONOate diethylammonium salt

[英文别名 ]:

DEA NONOate DEA NO diethylammonium salt
Diethylamine NONOate diethylammonium salt
DEA/NO diethylammonium salt

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 感染

信号通路 >> 抗感染 >> 细菌

[参考文献]

[1]. Sysel AM, et al. Antimicrobial properties of diethylamine NONOate, a nitric oxide donor, against Escherichia coli: a pilot study. J Antibiot (Tokyo). 2021 Apr;74(4):260-265.

[2]. Du ZY, et al. The nitric oxide donor, diethylamine NONOate, enhances preservation of the donor rat heart. J Heart Lung Transplant. 1998 Nov;17(11):1113-20.

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐物理化学性质

[ 分子式 ]:
C₈H₂₂N₄O₂

[ 分子量 ]:
206.29

[ 精确质量 ]:
206.174271

[ PSA ]:
75.58000

[ LogP ]:
0.31400

[ 外观性状 ]:
固体

[ 储存条件 ]:
20°C

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H315-H318-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
C

[ 风险声明 (欧洲) ]:
22-37/38-41

[ 安全声明 (欧洲) ]:
26-39

[ 危险品运输编码 ]:
NONH for all modes of transport

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐文献

Characterization of unusual truncated hemoglobins of Chlamydomonas reinhardtii suggests specialized functions.

Planta 242 , 167-85, (2015)

Annotated hemoglobin genes in Chlamydomonas reinhardtii form functional globins, despite unusual architectures. Spectral characteristics show subtle biochemical differences. Multiple globins might hel...

Structure Guided Chemical Modifications of Propylthiouracil Reveal Novel Small Molecule Inhibitors of Cytochrome b5 Reductase 3 That Increase Nitric Oxide Bioavailability.

J. Biol. Chem. 290 , 16861-72, (2015)

NADH cytochrome b5 reductase 3 (CYB5R3) is critical for reductive reactions such as fatty acid elongation, cholesterol biosynthesis, drug metabolism, and methemoglobin reduction. Although the physiolo...

Site-specific Effects of DUOX1-Related Peroxidase on Intercellular Apoptosis Signaling.

Anticancer Res. 35 , 5955-71, (2015)

Intercellular apoptosis-inducing HOCl signaling is known as an interplay between superoxide anions/H₂O₂ of transformed target cells and dual oxidase 1 (DUOX1)-related peroxidase that is released from ...

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2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐用途

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐名称

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐生物活性

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐物理化学性质

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐安全信息

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐文献

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相关化合物

2-(N,N-二乙基氨基)-二氮烯-2-氧 二乙铵盐

2-(N,N-二乙基氨基)-二氮烯-2-氧 二乙铵盐用途

2-(N,N-二乙基氨基)-二氮烯-2-氧 二乙铵盐名称

2-(N,N-二乙基氨基)-二氮烯-2-氧 二乙铵盐生物活性

2-(N,N-二乙基氨基)-二氮烯-2-氧 二乙铵盐物理化学性质

2-(N,N-二乙基氨基)-二氮烯-2-氧 二乙铵盐安全信息

2-(N,N-二乙基氨基)-二氮烯-2-氧 二乙铵盐文献

推荐生产厂家/供应商：

相关化合物

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐用途

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐名称

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐生物活性

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐物理化学性质

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐安全信息

2-(N,N-二乙基氨基)-二氮烯-2-氧二乙铵盐文献