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(R)-(-)-alpha-甲氧基苯乙酸

(R)-(-)-alpha-甲氧基苯乙酸名称

[ CAS 号 ]:
3966-32-3

[ 中文名 ]:
(R)-(-)-α-甲氧基苯乙酸

[ 英文名 ]:
(2S)-Methoxy(phenyl)acetic acid

[中文别名 ]:

[英文别名 ]:

(R)-(-)-α-Methoxyphenylacetic acid
(2S)-Methoxy(phenyl)acetic acid
(R)-2-Methoxy-2-phenylacetic acid
(R)-(-)-alpha-Methoxyphenylacetic Acid
Benzeneacetic acid, α-methoxy-, (αR)-
EINECS 223-580-9
(2R)-methoxy(phenyl)ethanoic acid
MFCD00004250
(2R)-Methoxy(phenyl)acetic acid
Benzeneacetic acid, α-methoxy-, (αS)-

(R)-(-)-alpha-甲氧基苯乙酸物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
283.8±0.0 °C at 760 mmHg

[ 熔点 ]:
64-67ºC

[ 分子式 ]:
C₉H₁₀O₃

[ 分子量 ]:
166.174

[ 闪点 ]:
116.1±15.3 °C

[ 精确质量 ]:
166.062988

[ PSA ]:
46.53000

[ LogP ]:
1.29

[ 外观性状 ]:
白色细结晶粉末或针状

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.535

[ 储存条件 ]:
室温，密封

[ 水溶解性 ]:
可溶于：甲醇

(R)-(-)-alpha-甲氧基苯乙酸MSDS

(R)-(-)-alpha-甲氧基苯乙酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2918990090

(R)-(-)-alpha-甲氧基苯乙酸合成路线

(R)-(-)-alpha-甲氧基苯乙酸上下游产品

(R)-(-)-alpha-甲氧基苯乙酸上游产品

(R)-(-)-alpha-甲氧基苯乙酸下游产品

(R)-(-)-alpha-甲氧基苯乙酸海关

[ 海关编码 ]: 2918990090

[ 中文概述 ]:
2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

(R)-(-)-alpha-甲氧基苯乙酸文献

Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.

Bioorg. Med. Chem. 22(17) , 4968-97, (2014)

TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led t...

B.M. Trost et al.

J. Org. Chem. 51 , 2370, (1986)

J. Org. Chem. 59 , 4202, (1994)

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