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盐酸哈尔酚

盐酸哈尔酚名称

[ CAS 号 ]:
40580-83-4

[ 中文名 ]:
盐酸哈尔酚

[ 英文名 ]:
HARMOL HYDROCHLORIDE

[英文别名 ]:

Harmol hydrochloride monohydrate
EINECS 254-980-1
HARMOL HCL

盐酸哈尔酚物理化学性质

[ 沸点 ]:
552.7ºC at 760 mmHg

[ 分子式 ]:
C₁₂H₁₁ClN₂O

[ 分子量 ]:
234.68200

[ 闪点 ]:
255ºC

[ 精确质量 ]:
234.05600

[ PSA ]:
48.91000

[ LogP ]:
3.53210

[ 储存条件 ]:
-20°C，避光干燥

盐酸哈尔酚MSDS

详细MSDS(安全技术说明书)

盐酸哈尔酚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV1048000

CHEMICAL NAME :: 9H-Pyrido(3,4-b)indol-7-ol, 1-methyl-, hydrochloride

CAS REGISTRY NUMBER :: 40580-83-4

LAST UPDATED :: 199012

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C12-H10-N2-O.Cl-H

MOLECULAR WEIGHT :: 234.70

WISWESSER LINE NOTATION :: T B656 EN HMJ F1 KQ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 4,33,1931

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 4,33,1931

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Behavioral - food intake (animal) Cardiac - pulse rate increase, without fall in BP Cardiac - pulse rate

REFERENCE :: QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 4,33,1931

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 280 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 4,33,1931

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - ataxia Cardiac - cardiomyopathy including infarction

REFERENCE :: QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 4,33,1931

盐酸哈尔酚安全信息

[ 安全声明 (欧洲) ]:
S24/25

[ 海关编码 ]:
2933990090

盐酸哈尔酚海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%