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芬苯达唑

芬苯达唑用途

【用途一】
为新的广谱兽用驱虫药。适用于驱除牛、马、猪、绵羊的胃肠道线虫成虫和幼虫,具有驱虫谱广、毒性低、耐受性好、适口性好、安全范围宽等优点。
【用途二】
该品为广谱驱虫药,具有驱虫谱广,毒性代,耐受性好,安全范围宽,适口性好等优点,为目前国外广泛应用的兽用驱虫药。本品对绵羊,马,猪的胃肠道线虫成虫和幼虫,口服单剂3.5-5mg/kg,减虫率为99-100%。对绵羊肝片吸虫(剂量为20mg/kg)、莫尼茨绦虫(剂量为5-10mg/kg)减虫率几乎达100%。
【用途三】
该品味广谱驱虫药,具有驱虫谱广,毒性代,耐受性好,安全范围宽,适口性好等优点,为目前国外广泛应用的兽用驱虫药。本品对绵羊,马、猪的胃肠道线虫成虫和幼虫,口服单剂3.5-5mg/L,减虫率为99-100%。对绵羊管盘吸虫(剂量为20mg/kg);莫尼茨绦虫(剂量为5-10mg/L)减虫率几乎达到100%。

芬苯达唑名称

[ CAS 号 ]:
43210-67-9

[ 中文名 ]:
芬苯达唑

[ 英文名 ]:
fenbendazole

[中文别名 ]:

[英文别名 ]:

芬苯达唑生物活性

芬苯达唑物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
541.4±42.0 °C at 760 mmHg

[ 熔点 ]:
233°C

[ 分子式 ]:
C15H13N3O2S

[ 分子量 ]:
299.348

[ 闪点 ]:
281.2±27.9 °C

[ 精确质量 ]:
299.072845

[ PSA ]:
92.31000

[ LogP ]:
4.34

[ 外观性状 ]:
白色至淡黄色粉末

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.679

[ 储存条件 ]:
0-6°C

[ 水溶解性 ]:
水溶性:不溶

芬苯达唑MSDS

芬苯达唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DD6520500
CHEMICAL NAME :
2-Benzimidazolecarbamic acid, 5-(phenylthio)-, methyl ester
CAS REGISTRY NUMBER :
43210-67-9
LAST UPDATED :
199606
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C15-H13-N3-O2-S
MOLECULAR WEIGHT :
299.37
WISWESSER LINE NOTATION :
T56 BM DNJ CMVO1 GSR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - pig
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
42 gm/kg/14D-I
TOXIC EFFECTS :
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Human Cells - not otherwise specified
DOSE/DURATION :
2 mg/L
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 31,505,1976

芬苯达唑安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
DD6520500

[ 海关编码 ]:
2933990090

芬苯达唑合成路线

芬苯达唑上下游产品

芬苯达唑制备

【方法一】
由5-氯-2-硝基苯胺与苯硫醇反应,制得5-苯硫基-2-硝基苯胺,收率91%。经硫酸亚铁-铁粉还原得3-苯硫基邻苯二胺,收率90%。最后与S-甲基-氰胺基甲酸甲酯环合得到苯硫苯咪唑。

芬苯达唑海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

芬苯达唑文献

Development and validation of an ultra high performance liquid chromatography tandem mass spectrometry method for simultaneous determination of sulfonamides, quinolones and benzimidazoles in bovine milk.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 962 , 20-9, (2014)

A simple, sensitive and reliable analytical method was developed for the simultaneous determination of 38 veterinary drugs (18 sulfonamides, 11 quinolones and 9 benzimidazoles) and 8 metabolites of be...

Epidemiology. Opposite effects of anthelmintic treatment on microbial infection at individual versus population scales.

Science 347(6218) , 175-7, (2015)

Parasitic worms modulate host immune responses in ways that affect microbial co-infections. For this reason, anthelmintic therapy may be a potent tool for indirectly controlling microbial pathogens. H...

Enantiomeric behaviour of albendazole and fenbendazole sulfoxides in domestic animals: pharmacological implications.

Vet. J. 181(3) , 241-50, (2009)

Albendazole and fenbendazole are methylcarbamate benzimidazole anthelmintics extensively used to control gastrointestinal parasites in domestic animals. These parent compounds are metabolised to alben...


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公司名:上海化源世纪贸易有限公司

区域:上海市普陀区

价格:

联系人:徐经理

产品详情:芬苯达唑


公司名:南通润丰石油化工有限公司

区域:南通市崇川区

价格:
¥需询单/1kg ¥需询单/1ton

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公司名:上海吉至生化科技有限公司

区域:上海市奉贤区

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¥148.0/100mg

联系人:刘佳

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公司名:上海源溪生物科技有限公司

区域:上海市浦东新区

价格:
¥需询单/1g

联系人:赖经理

产品详情:Fenbendazole (Panacur)


公司名:上海脉铂医药科技有限公司

区域:上海市嘉定区

价格:
¥849.0/500mg ¥499.0/1g ¥479.0/100mg ¥需询单/1g

联系人:李先生

产品详情:Fenbendazole


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相关化合物

【芬苯达唑】化源网提供芬苯达唑CAS号43210-67-9,芬苯达唑MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询芬苯达唑上化源网,专业又轻松。>>电脑版:芬苯达唑

标题:芬苯达唑_MSDS_用途_密度_芬苯达唑CAS号【43210-67-9】_化源网 地址:https://www.chemsrc.com/amp/cas/43210-67-9_946913.html