(-)-Epipodophyllotoxin
(-)-Epipodophyllotoxin用途
(-)-Epipodophyllotoxin名称
[ CAS 号 ]:
4375-07-9
[ 中文名 ]:
表鬼臼毒素
[ 英文名 ]:
Epipodophyllotoxin
[英文别名 ]:
- Sunphenon EGC
- Epipodophyllotoxin
- EPIGALLOCATECHIN
- Teacatechin II
- epi
- Galloepicatechin
- epigallocatechol
- Greenteacatechins
(-)-Epipodophyllotoxin生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
(-)-Epipodophyllotoxin物理化学性质
[ 密度 ]:
1.37g/cm3
[ 沸点 ]:
597.9ºC at 760 mmHg
[ 熔点 ]:
160.3 °C
[ 分子式 ]:
C22H22O8
[ 分子量 ]:
414.40500
[ 闪点 ]:
210.2ºC
[ 精确质量 ]:
414.13100
[ PSA ]:
92.68000
[ LogP ]:
2.40920
[ 外观性状 ]:
白色或类白色结晶粉末
[ 折射率 ]:
1.605
[ 储存条件 ]:
2-8°C,密封,干燥
(-)-Epipodophyllotoxin毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LV2520000
- CAS REGISTRY NUMBER :
- 4375-07-9
- BEILSTEIN REFERENCE NO. :
- 0099162
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C22-H22-O8
- MOLECULAR WEIGHT :
- 414.44
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 135 mg/kg
- SEX/DURATION :
- female 25 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - menstrual cycle changes or disorders
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 20 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 48,512,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5374 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 214 (estimated) No. of Female Employees: 214 (estimated)
(-)-Epipodophyllotoxin上下游产品
(-)-Epipodophyllotoxin上游产品
(-)-Epipodophyllotoxin下游产品
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相关化合物
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