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3-氟-DL-苯丙氨酸

3-氟-DL-苯丙氨酸用途

H-DL-Phe(3-F)-OH是苯丙氨酸衍生物[1]。

3-氟-DL-苯丙氨酸名称

[ CAS 号 ]:
456-88-2

[ 中文名 ]:
3-氟-DL-苯丙氨酸

[ 英文名 ]:
3-Fluoro-DL-phenylalanine

[中文别名 ]:

[英文别名 ]:

3-FLUORO-DL-PHENYLALANINE
EINECS 207-272-1
DL-2-Amino-3-(3-fluorophenyl)propionic acid
2-Amino-3-(3-fluorophenyl)propionic Acid
2-Amino-3-(3-fluorophenyl)propanoic acid
QVYZ1R CF &&DL Form
DL-(3-Fluorophenyl)alanine
m-Fluoro-DL-phenylalanine
m-Fluorophenylalanine
MFCD00004273

3-氟-DL-苯丙氨酸生物活性

[ 描述 ]:

H-DL-Phe(3-F)-OH是苯丙氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-819.

3-氟-DL-苯丙氨酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
305.0±32.0 °C at 760 mmHg

[ 熔点 ]:
-240ºC(dec.)

[ 分子式 ]:
C₉H₁₀FNO₂

[ 分子量 ]:
183.180

[ 闪点 ]:
138.3±25.1 °C

[ 精确质量 ]:
183.069550

[ PSA ]:
63.32000

[ LogP ]:
1.16

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.555

[ 储存条件 ]:
室温，干燥

3-氟-DL-苯丙氨酸MSDS

详细MSDS(安全技术说明书)

3-氟-DL-苯丙氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY6300000

CHEMICAL NAME :: Alanine, 3-(m-fluorophenyl)-

CAS REGISTRY NUMBER :: 456-88-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H10-F-N-O2

MOLECULAR WEIGHT :: 183.20

WISWESSER LINE NOTATION :: QVYZ1R CF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 73,176,1941

3-氟-DL-苯丙氨酸安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R37

[ 安全声明 (欧洲) ]:
24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2922499990

3-氟-DL-苯丙氨酸上下游产品

3-氟-DL-苯丙氨酸上游产品

3-氟-DL-苯丙氨酸下游产品

3-氟-DL-苯丙氨酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

3-氟-DL-苯丙氨酸文献

Hidden overflow pathway to L-phenylalanine in Pseudomonas aeruginosa.

J. Bacteriol. 154(2) , 623-31, (1983)

Pseudomonas aeruginosa is representative of a large group of pseudomonad bacteria that possess coexisting alternative pathways to L-phenylalanine (as well as to L-tyrosine). These multiple flow routes...

19F n.m.r. studies of conformational changes accompanying cyclic AMP binding to 3-fluorophenylalanine-containing cyclic AMP receptor protein from Escherichia coli.

Biochem. J. 287 ( Pt 2) , 627-32, (1992)

A fluorine-containing analogue of the cyclic AMP (cAMP) receptor protein (CRP) from Escherichia coli was prepared by biosynthetic incorporation of 3-fluorophenylalanine (3-F-Phe). 19F n.m.r. studies o...

Fluorine-19 nuclear magnetic resonance spectroscopic study of fluorophenylalanine- and fluorotryptophan-labeled avian egg white lysozymes.

Biochemistry 33(17) , 5238-45, (1994)

We report the 470-MHz (11.7 T) 19F solution nuclear magnetic resonance (NMR) spectra of 2-, 3-, and 4-fluorophenylalanine incorporated into the egg white lysozymes (EC 3.2.1.17) of chicken, pheasant, ...

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