<生产厂家价格>

1,5-二氨基戊烷

1,5-二氨基戊烷用途

用作有机合成中间体、环氧树脂固化剂，用于高聚物制备，也用于生物研究。

1,5-二氨基戊烷名称

[ CAS 号 ]:
462-94-2

[ 中文名 ]:
1,5-二氨基戊烷

[ 英文名 ]:
Cadaverine

[中文别名 ]:

[英文别名 ]:

1,5-Pentamethylenediamine
EINECS 207-329-0
Pentamethylenediamine
MFCD00008239
1,5-Pentanediamine
Pentane-1,5-diamine
1,5-Diaminopentane
Z5Z

1,5-二氨基戊烷物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
179.0±8.0 °C at 760 mmHg

[ 熔点 ]:
9 °C

[ 分子式 ]:
C₅H₁₄N₂

[ 分子量 ]:
102.178

[ 闪点 ]:
76.5±24.8 °C

[ 精确质量 ]:
102.115700

[ PSA ]:
52.04000

[ LogP ]:
-0.49

[ 外观性状 ]:
透明无色液体带有一种恶臭

[ 蒸汽压 ]:
1.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.458

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类、食品化工添加剂分开存放

[ 稳定性 ]:
Stable. Incompatible with acid chlorides, acids, acid anhydrides, strong oxidizing agents, carbon dioxide.

[ 水溶解性 ]:
soluble

1,5-二氨基戊烷MSDS

1,5-二氨基戊烷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SA0200000

CHEMICAL NAME :: 1,5-Pentanediamine

CAS REGISTRY NUMBER :: 462-94-2

BEILSTEIN REFERENCE NO. :: 1697256

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C5-H14-N2

MOLECULAR WEIGHT :: 102.21

WISWESSER LINE NOTATION :: Z5Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Rectal

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 200 mmol/L

REFERENCE :: IJRBA3 International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. (Taylor & Francis Inc., 242 Cherry St., Philadelphia, PA 19106) V.1- 1959- Volume(issue)/page/year: 9,185,1965

1,5-二氨基戊烷安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314

[ 补充危害声明 ]:
Repeated exposure may cause skin dryness or cracking.

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S25

[ 危险品运输编码 ]:
UN 2735 8/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
SA0200000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2921290000

1,5-二氨基戊烷合成路线

1,5-二氨基戊烷上下游产品

1,5-二氨基戊烷上游产品

1,5-二氨基戊烷下游产品

1,5-二氨基戊烷制备

由赖氨酸脱羧而得。实验室制备可从戊二腈出发：将戊二腈的无水乙醇溶液煮沸后，以较快的速度加入金属钠，反应完后加入水，将乙醇蒸出，剩余的反应物用过热蒸汽蒸馏。馏出物用稀盐酸中和，蒸干，剩余物以冷无水乙醇洗涤，再用少量固体氢氧化钾及水分解所得的盐酸盐，蒸去水，减压蒸馏，即得尸胺。

1,5-二氨基戊烷海关

[ 海关编码 ]: 2921290000

[ 中文概述 ]:
2921290000. 其他无环多胺及其衍生物及它们的盐. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

1,5-二氨基戊烷文献

In vitro inhibition of lysine decarboxylase activity by organophosphate esters.

Biochem. Pharmacol. 92(3) , 506-16, (2014)

Organophosphate esters (OPEs), a major group of organophosphorus flame retardants, are regarded as emerging environmental contaminants of health concern. Amino acid decarboxylases catalyze the convers...

Mechanistic studies on the flavin-dependent N⁶-lysine monooxygenase MbsG reveal an unusual control for catalysis.

Arch. Biochem. Biophys. 550-551 , 58-66, (2014)

The mechanism of Mycobacterium smegmatis G (MbsG), a flavin-dependent l-lysine monooxygenase, was investigated under steady-state and rapid reaction conditions using primary and solvent kinetic isotop...

Optimization of Direct Lysine Decarboxylase Biotransformation for Cadaverine Production with Whole-Cell Biocatalysts at High Lysine Concentration.

J. Microbiol. Biotechnol. 25 , 1108-13, (2015)

Cadaverine (1,5-diaminopentane) is an important industrial chemical with a wide range of applications. Although there have been many efforts to produce cadaverine through fermentation, there are not m...

更多文献