乙烯菌核利

乙烯菌核利用途

保护性触杀型杀菌剂。对作物安全，能有效防治菌核病、灰霉病，能有效杀死灰霉菌、核盘蓖、连椹菌，并有兼治其他真菌的作用。如蔬菜立枯菌、白斑病菌、亚隔孢壳菌以及观赏植物上的壳多孢菌和座盘菌。能抑制病菌孢子萌发和芽管生长。对葡萄、蔬菜还有治螨作用。通常用量为每百平方米50%可湿性粉剂11.3～15g。在番茄和黄瓜上使用安全间隔期为21～35d。
该品为接触性杀菌剂，对葡萄灰霉病，苹果、梨灰霉病有良好的防治效果

乙烯菌核利名称

[ CAS 号 ]:
50471-44-8

[ 中文名 ]:
乙烯菌核利

[ 英文名 ]:
Vinclozoline

[中文别名 ]:

[英文别名 ]:

Caswell No. 323C
Vinclozoline
Vinchlozoline
Ronilan
Ornalin
UNII:JJ258EZN1I
Vorlan
MFCD00055511
Vinclozolin
EINECS 256-599-6

乙烯菌核利物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
369.9±52.0 °C at 760 mmHg

[ 熔点 ]:
108ºC

[ 分子式 ]:
C₁₂H₉Cl₂NO₃

[ 分子量 ]:
286.111

[ 闪点 ]:
177.5±30.7 °C

[ 精确质量 ]:
284.995941

[ PSA ]:
46.61000

[ LogP ]:
3.19

[ 外观性状 ]:
无色晶体带有一种淡芳香气味

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.640

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

乙烯菌核利MSDS

详细MSDS(安全技术说明书)

乙烯菌核利毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RP8530000

CHEMICAL NAME :: 2,4-Oxazolidinedione, 3-(3,5-dichlorophenyl)-5-methyl-5-vinyl-

CAS REGISTRY NUMBER :: 50471-44-8

LAST UPDATED :: 199701

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C12-H9-Cl2-N-O3

MOLECULAR WEIGHT :: 286.12

WISWESSER LINE NOTATION :: T5OVNV EHJ CR CG EG& E1U1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >29100 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1170 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 8 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7700 mg/kg/11W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in adrenal weight Related to Chronic Data - changes in testicular weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 1134 mg/kg/7D-C

TOXIC EFFECTS :: Liver - changes in liver weight Gastrointestinal - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1100 mg/kg

SEX/DURATION :: female 14-21 day(s) after conception lactating female 3 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - germ cell effects (in offspring)

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - mouse Fibroblast

DOSE/DURATION :: 25 mg/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 21,81,1993 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

乙烯菌核利安全信息

[ 符号 ]:

GHS07, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H317-H351-H360-H411

[ 警示性声明 ]:
P201-P273-P280-P308 + P313

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T,N,Xn,F

[ 风险声明 (欧洲) ]:
60-61-40-43-51/53-36-20/21/22-11

[ 安全声明 (欧洲) ]:
53-45-61-36-26-16

[ 危险品运输编码 ]:
UN3077 9/PG 3

[ RTECS号 ]:
RP8530000

[ 包装等级 ]:
II

[ 危险类别 ]:
3

[ 海关编码 ]:
2934999039

乙烯菌核利制备

由3，5-二氯苯胺光气化制成3，5-二氯苯基异氰酸酯，再与α-乙烯基乳酸乙酯在三乙胺存在下，在苯溶剂中进行回流反应，制得乙烯菌核利。

乙烯菌核利海关

[ 海关编码 ]: 2934999039

[ 中文概述 ]:
2934999039 棉隆,乙烯菌核利。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: S.进出口农药登记证明

[ Summary ]:
2934999039 3,5-dimethyl-1,3,5-thiadiazinane-2-thione。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

乙烯菌核利文献

Anti-androgen vinclozolin impairs sperm quality and steroidogenesis in goldfish.

Aquat. Toxicol. 122-123 , 181-7, (2012)

In mammals, vinclozolin (VZ) is known as anti-androgen, which causes male infertility via androgen receptor (AR) antagonism. In aquatic animals, the VZ effects on reproductive functions are largely un...

LC-MS analysis of the plasma metabolome--a novel sample preparation strategy.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 978-979 , 83-8, (2015)

Blood plasma is a well-known body fluid often analyzed in studies on the effects of toxic compounds as physiological or chemical induced changes in the mammalian body are reflected in the plasma metab...

Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis.

Toxicol. Sci. 141(1) , 78-89, (2014)

In the present study, a previously established integrated testing strategy (ITS) for in vitro estrogenicity testing was extended with additional in vitro assays in order to broaden its sensitivity to ...

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