醋霉素

醋霉素用途

Acetomycin是一种抗生素。Acetomycin 抑制 CT-8 人结肠腺癌细胞 (IC50: 1.5 μg/mL) 和 L1210 鼠白血病细胞 (IC50: 2.2 μg/mL) 的生长。Acetomycin 可从放线菌 WP-2661 中分离出来。

醋霉素名称

[ CAS 号 ]:
510-18-9

[ 中文名 ]:
醋霉素

[ 英文名 ]:
Acetomycin

[英文别名 ]:

acetomycin

醋霉素生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

[参考文献]

[1]. Mamber SW, et al. Biological effects of acetomycin. I. Activity against tumor cells in vitro and in vivo. J Antibiot (Tokyo). 1987 Jan;40(1):73-6.

醋霉素物理化学性质

[ 密度 ]:
1.18g/cm3

[ 沸点 ]:
336.2ºC at 760mmHg

[ 分子式 ]:
C₁₀H₁₄O₅

[ 分子量 ]:
214.22

[ 闪点 ]:
148.9ºC

[ 精确质量 ]:
214.08400

[ PSA ]:
69.67000

[ LogP ]:
0.66380

[ 折射率 ]:
1.466

醋霉素毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AL2850000

CHEMICAL NAME :: Acetomycin

CAS REGISTRY NUMBER :: 510-18-9

BEILSTEIN REFERENCE NO. :: 0174279

LAST UPDATED :: 199709

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H14-O5

MOLECULAR WEIGHT :: 214.24

WISWESSER LINE NOTATION :: T5OVTJ CV1 C1 D1 EOV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 2,905,1978

醋霉素安全信息

[ 海关编码 ]:
2932190090

醋霉素海关

[ 海关编码 ]: 2932190090

[ 中文概述 ]:
2932190090 其他结构上有非稠合呋喃环化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

醋霉素