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Isoxanthohumol

Isoxanthohumol用途

异黄腐酚是一种来自啤酒花和啤酒的异戊二烯基类黄酮。异黄腐酚对几种人类癌细胞系具有抗增殖活性。异黄腐酚抑制肿瘤激发动物肺转移灶的形成。异黄腐酚对疱疹病毒(HSV1和HSV2)和牛病毒性腹泻病毒(BVDV)具有抗病毒活性[1][2]。

Isoxanthohumol名称

[ CAS 号 ]:
521-48-2

[ 英文名 ]:
Isoxanthohumol

[英文别名 ]:

4',7-DIHYDROXY-5-METHOXY-8-PRENYLFLAVANONE
Isoxanthohumol

Isoxanthohumol生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 抗感染 >> HSV

研究领域 >> 感染

[ 靶点 ]

HSV-1

HSV-2

[参考文献]

[1]. Żołnierczyk AK, et al. Isoxanthohumol--Biologically active hop flavonoid. Fitoterapia. 2015 Jun;103:71-82.

[2]. Krajnović T, et al. The hop-derived prenylflavonoid isoxanthohumol inhibits the formation of lung metastasis in B16-F10 murine melanoma model. Food Chem Toxicol. 2019 Jul;129:257-268.

Isoxanthohumol物理化学性质

[ 分子式 ]:
C₂₁H₂₂O₅

[ 分子量 ]:
354.39600

[ 精确质量 ]:
354.14700

[ PSA ]:
75.99000

[ LogP ]:
4.32160

[ 储存条件 ]:
-20°C，密闭，干燥

IsoxanthohumolMSDS

Isoxanthohumol安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2932999099

Isoxanthohumol合成路线

Isoxanthohumol上下游产品

Isoxanthohumol上游产品

Isoxanthohumol下游产品

Isoxanthohumol海关

[ 海关编码 ]: 2932999099

[ 中文概述 ]:
2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Isoxanthohumol文献

A comprehensive characterisation of beer polyphenols by high resolution mass spectrometry (LC-ESI-LTQ-Orbitrap-MS).

Food Chem. 169 , 336-43, (2014)

Beer is the second most consumed alcoholic beverage in Europe and shown by the European Prospective Investigation into Cancer and Nutrition cohort study to be the main food contributor to hydroxybenzo...

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