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1-O-十六烷基-SN-甘油基-3-胆碱磷酸

1-O-十六烷基-SN-甘油基-3-胆碱磷酸用途

Lyso PAF C-16是溶浆菌素(LysoPls)特异性磷脂酶D(LysoPLD)的底物。Lyso PAF C-16与花生四烯酸选择性乙酰化[1][2]。

1-O-十六烷基-SN-甘油基-3-胆碱磷酸名称

[ CAS 号 ]:
52691-62-0

[ 中文名 ]:
1-O-十六烷基-SN-甘油基-3-胆碱磷酸

[ 英文名 ]:
lysophosphatidylcholine O-16:0/0:0

[中文别名 ]:

1-O-十六烷基-sn-甘油基-3-胆碱磷酸

[英文别名 ]:

LYSO-PAF16
1-hexadecyl-sn-glycero-3-phosphocholine
1-hexadecyl
1-O-hexadecyl lyso PAF
C16 LYSO PAF
1-O-hexadecyl lyso platelet-activating factor
1-O-PALMITYL-SN-GLYCERO-3-PHOSPHOCHOLINE
lysophosphatidylcholine O-16:0/0:0
1-O-hexadecyl-2-lyso-sn-glycero-3-phosphocholine
LYSO-PLATELET ACTIVATING FACTOR

1-O-十六烷基-SN-甘油基-3-胆碱磷酸生物活性

[ 描述 ]:

Lyso PAF C-16是溶浆菌素(LysoPls)特异性磷脂酶D(LysoPLD)的底物。Lyso PAF C-16与花生四烯酸选择性乙酰化[1][2]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Venable ME, et al. Enzymatic studies of lyso platelet-activating factor acylation in human neutrophils and changes upon stimulation. J Biol Chem. 1993 Apr 15;268(11):7965-75.

[2]. Yamaura S, et al. Novel enzymatic method for assaying Lp-PLA2 in serum. Clin Chim Acta. 2018 Jun;481:184-188.

1-O-十六烷基-SN-甘油基-3-胆碱磷酸物理化学性质

[ 分子式 ]:
C₂₄H₅₂NO₆P

[ 分子量 ]:
481.647

[ 精确质量 ]:
481.353210

[ PSA ]:
97.86000

[ LogP ]:
3.23

[ 外观性状 ]:
白色固体

[ 储存条件 ]:
-20°C，密闭，干燥

1-O-十六烷基-SN-甘油基-3-胆碱磷酸MSDS

详细MSDS(安全技术说明书)

1-O-十六烷基-SN-甘油基-3-胆碱磷酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 风险声明 (欧洲) ]:
R10;R21

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2923900090

1-O-十六烷基-SN-甘油基-3-胆碱磷酸上下游产品

1-O-十六烷基-SN-甘油基-3-胆碱磷酸上游产品

1-O-十六烷基-SN-甘油基-3-胆碱磷酸下游产品

1-O-十六烷基-SN-甘油基-3-胆碱磷酸海关

[ 海关编码 ]: 2923900090

[ 中文概述 ]:
2923900090 其他季铵盐及季铵碱。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

1-O-十六烷基-SN-甘油基-3-胆碱磷酸文献

Metabolism of platelet-activating factor by rat alveolar macrophages: lyso-PAF as an obligatory intermediate in the formation of alkylarachidonoyl glycerophosphocholine species.

Biochim. Biophys. Acta 837 , 52, (1985)

1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine (alkylacetyl-GPC; platelet-activating factor; PAF) is actively taken up and metabolized by rat alveolar macrophages maintained in culture. The major metabo...

Myocardial dysfunction and coronary vasoconstriction induced by platelet-activating factor in the post-infarcted rabbit isolated heart.

J. Mol. Cell. Cardiol. 20(6) , 547-61, (1988)

Myocardial injury was produced in separated groups of anesthetized rabbits by occlusion of the left circumflex coronary artery for 1 h followed by reperfusion for 2, 4, or 6 h after release of the occ...

Metabolism of platelet activating factor (PAF) and related ether lipids by neonatal rat myocytes.

J. Lipid Mediat. 1(2) , 113-23, (1989)

Suspensions of neonatal rat myocytes were used to investigate the metabolism of [3H]PAF (1-alkyl-2-acetyl-(sn-glycero-3-phosphocholine) (GPC] and [3H]alkyllyso-GPC. [3H]Alkylacyl-GPC consisting of mol...

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