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L-木酮糖

L-木酮糖用途

L-木糖是一种存在于血液、脑脊液和尿液中的内源性代谢产物,可用于核糖5磷酸异构酶缺乏症的研究[1][2]。

L-木酮糖名称

[ CAS 号 ]:
527-50-4

[ 中文名 ]:
L-木酮糖

[ 英文名 ]:
L-(+)-Ribulose

[中文别名 ]:

L-苏-五酮糖

[英文别名 ]:

L-Xylulose - Aqueous solution
D-threo-2-Pentulofuranose
L-Ribulose
L-Riboketose
Lg-tartaric acid bis-pentylamide
L-erythro-2-Pentulose
Xylulofuranose
L-erythro-Pentulose
Ribulose
L-Arabinoketose

L-木酮糖生物活性

[ 描述 ]:

L-木糖是一种存在于血液、脑脊液和尿液中的内源性代谢产物,可用于核糖5磷酸异构酶缺乏症的研究[1][2]。

[ 相关类别 ]:

研究领域 >> 心血管疾病

[ 靶点 ]

Human Endogenous Metabolite

[体外研究]

内源性代谢产物被定义为《京都基因和基因组百科全书》注释为我们基因组中约1900种代谢酶的底物或产物。在文献正文中很清楚,许多这些代谢产物都具有毒性[1]。

[参考文献]

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.

[2]. Huck JH, et al. Ribose-5-phosphate isomerase deficiency: new inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy. Am J Hum Genet. 2004 Apr;74(4):745-51.

L-木酮糖物理化学性质

[ 密度 ]:
1.7±0.1 g/cm3

[ 沸点 ]:
364.2±42.0 °C at 760 mmHg

[ 分子式 ]:
C₅H₁₀O₅

[ 分子量 ]:
150.130

[ 闪点 ]:
174.1±27.9 °C

[ 精确质量 ]:
150.052826

[ PSA ]:
90.15000

[ LogP ]:
-0.78

[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C

[ 折射率 ]:
1.624

L-木酮糖安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 海关编码 ]:
2914400090

L-木酮糖合成路线

详细合成路线

L-木酮糖上下游产品

L-木酮糖上游产品

L-木酮糖下游产品

L-木酮糖海关

[ 海关编码 ]: 2914400090

[ 中文概述 ]:
2914400090 其他酮醇及酮醛。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

L-木酮糖文献

Construction and co-expression of plasmid encoding xylitol dehydrogenase and a cofactor regeneration enzyme for the production of xylitol from D-arabitol.

Enzyme Microb. Technol. 51(2) , 119-24, (2012)

The biotransformation of D-arabitol into xylitol was investigated with focus on the conversion of D-xylulose into xylitol. This critical conversion was accomplished using Escherichia coli to co-expres...

Cloning and characterization of a novel NAD+ -dependent xylitol dehydrogenase from Gluconobacter oxydans CGMCC 1. 637.

Wei Sheng Wu Xue Bao 52(6) , 726-35, (2012)

To clone the xylitol dehydrogenase gene from Gluconobacter oxydans CGMCC 1.637, to characterize enigmatic properties of xylitol dehydrogenase and to investigate the induction abilities of various carb...

Gene cloning and characterization of L-ribulose 3-epimerase from Mesorhizobium loti and its application to rare sugar production.

Biosci. Biotechnol. Biochem. 77(3) , 511-5, (2013)

A gene encoding L-ribulose 3-epimerase (L-RE) from Mesorhizobium loti, an important enzyme for rare sugar production by the Izumoring strategy, was cloned and overexpressed. The enzyme showed highest ...

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