芳姜黄酮

芳姜黄酮用途

ar-Turmerone ((+)-ar-Turmerone) 是姜黄的主要生物活性成分,具有抗肿瘤和抗炎作用。ar-turmerone ((+)-ar-Turmerone) 能激活凋亡蛋白人类淋巴瘤 U937 细胞中。ar-Turmerone ((+)-ar-Turmerone) 对小鼠树突细胞具有正向调节作用,能诱导神经干细胞增殖,是一种很有前途的神经疾病治疗药物。

芳姜黄酮名称

[ CAS 号 ]:
532-65-0

[ 中文名 ]:
芳姜黄酮,来源于姜黄

[ 英文名 ]:
ar-Turmerone

[中文别名 ]:

[英文别名 ]:

Tumerone
(+)-ar-Turmerone
(S)-AR-TURMERONE

芳姜黄酮生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 细胞凋亡 >> 细胞凋亡

研究领域 >> 癌症

研究领域 >> 炎症/免疫

[参考文献]

[1]. Liju VB, et al. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L. Indian J Pharmacol. 2011 Sep;43(5):526-31.

[2]. Yue GG, et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2011-20.

[3]. Lee Y, et al. Activation of apoptotic protein in U937 cells by a component of turmeric oil. BMB Rep. 2009 Feb 28;42(2):96-100.

[4]. Yonggang T, et al. Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR). Hum Vaccin Immunother. 2012 Oct;8(10):1416-24.

[5]. Hucklenbroich J, et al. Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo. Stem Cell Res Ther. 2014 Sep 26;5(4):100.

芳姜黄酮物理化学性质

[ 沸点 ]:
326℃

[ 分子式 ]:
C₁₅H₂₀O

[ 分子量 ]:
216.31900

[ 精确质量 ]:
216.15100

[ PSA ]:
17.07000

[ LogP ]:
4.02390

[ 外观性状 ]:
液体

[ 储存条件 ]:
2-8℃，干燥，密闭

芳姜黄酮安全信息

[ 符号 ]:

GHS07, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H317-H319-H411

[ 警示性声明 ]:
P273-P280-P305 + P351 + P338

[ 危害码 (欧洲) ]:
Xi,N

[ 风险声明 (欧洲) ]:
36-43-51/53

[ 安全声明 (欧洲) ]:
36/37-61

[ 危险品运输编码 ]:
UN 3082 9 / PGIII

[ 海关编码 ]:
2914399090

芳姜黄酮合成路线

详细合成路线

芳姜黄酮上下游产品

芳姜黄酮上游产品

芳姜黄酮下游产品

芳姜黄酮海关

[ 海关编码 ]: 2914399090

[ 中文概述 ]:
2914399090. 其他不含其他含氧基的芳香酮. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

芳姜黄酮文献

Turmeric (Curcuma longa L.) volatile oil inhibits key enzymes linked to type 2 diabetes.

Int. J. Food Sci. Nutr. 63(7) , 832-4, (2012)

Anti-diabetic capacity of Curcuma longa volatile oil in terms of its ability to inhibit glucosidase activities was evaluated. Turmeric volatile oils inhibited glucosidase enzymes more effectively than...

Selective induction of apoptosis by ar-turmerone isolated from turmeric (Curcuma longa L) in two human leukemia cell lines, but not in human stomach cancer cell line.

Int. J. Mol. Med. 9(5) , 481-4, (2002)

We have investigated the effects of ar-turmerone isolated from turmeric (Curcuma longa L) on DNA of human leukemia cell lines, Molt 4B, HL-60 and stomach cancer KATO III cells. It was found that selec...

Induction of apoptosis by ar-turmerone on various cell lines.

Int. J. Mol. Med. 14(2) , 253-6, (2004)

This study investigated the cytotoxic effect of ar-turmerone isolated from turmeric (Curcuma longa L) on the K562, L1210, U937 and RBL-2H3 cell lines by the MTT assay. Ar-turmerone exhibited potent cy...

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