4-异丙基苯甲醇

4-异丙基苯甲醇用途

4-Isopropylbenzyl alcohol 是来自金花茶 (Camellia nitidissima) 叶和花的精油。C. nitidissima 具有多种生物活性,包括抗氧化活性,抗癌活性,细胞毒性,以及抑制晚期糖基化终产物的形成。

4-异丙基苯甲醇名称

[ CAS 号 ]:
536-60-7

[ 中文名 ]:
4-异丙基苯甲醇

[ 英文名 ]:
Cuminol

[中文别名 ]:

[英文别名 ]:

4-Isopropylbenzyl alcohol
Benzyl alcohol, p-isopropyl-
Cuminol
Cumic alcohol
p-Isopropylbenzyl alcohol
p-Cumic alcohol
Cuminic alcohol
Benzenemethanol, 4-(1-methylethyl)-
(4-Isopropylphenyl)methanol
[4-(Propan-2-Yl)Phenyl]Methanol

4-异丙基苯甲醇生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Wang B, et al. Essential oils and ethanol extract from Camellia nitidissima and evaluation of their biologicalactivity. J Food Sci Technol. 2018 Dec;55(12):5075-5081.

4-异丙基苯甲醇物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
249.0±0.0 °C at 760 mmHg

[ 熔点 ]:
28 °C

[ 分子式 ]:
C₁₀H₁₄O

[ 分子量 ]:
150.218

[ 闪点 ]:
106.0±3.7 °C

[ 精确质量 ]:
150.104462

[ PSA ]:
20.23000

[ LogP ]:
2.37

[ 外观性状 ]:
无色至淡黄色透明液体

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.524

[ 储存条件 ]:
室温

4-异丙基苯甲醇MSDS

4-异丙基苯甲醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GZ7260000

CHEMICAL NAME :: p-Cymen-7-ol

CAS REGISTRY NUMBER :: 536-60-7

BEILSTEIN REFERENCE NO. :: 0636665

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C10-H14-O

MOLECULAR WEIGHT :: 150.24

WISWESSER LINE NOTATION :: Q1R DY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,871,1974 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1020 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,871,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,871,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5142 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1557 (estimated) No. of Female Employees: 276 (estimated)

4-异丙基苯甲醇安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22;R38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
GZ7260000

[ 海关编码 ]:
2906299090

4-异丙基苯甲醇合成路线

4-异丙基苯甲醇制备

1.用枯茗醛在活性镍存在下催化氢化得到或用四氢硼钠还原制得。也可用对异丙基苯、多聚甲醛在氯化氢存在下催化缩合来制备等。

2.在活性镍存在下，由枯茗醛催化氢化得到。或者用对异丙基苯、多聚甲醛在氯化氢存在下催化缩合制得。

4-异丙基苯甲醇海关

[ 海关编码 ]: 2906299090

[ 中文概述 ]:
2906299090 其他芳香醇. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

4-异丙基苯甲醇文献

Anaerobic activation of p-cymene in denitrifying betaproteobacteria: methyl group hydroxylation versus addition to fumarate.

Appl. Environ. Microbiol. 80(24) , 7592-603, (2014)

The betaproteobacteria "Aromatoleum aromaticum" pCyN1 and "Thauera" sp. strain pCyN2 anaerobically degrade the plant-derived aromatic hydrocarbon p-cymene (4-isopropyltoluene) under nitrate-reducing c...

New mosquito repellent from Eucalyptus camaldulensis. Watanabe K, et al.

J. Agric. Food Chem. 41(11) , 2164-66, (1993)

Selective oxidation of alcohols to aldehydes and ketones over TiO₂-supported gold nanoparticles in supercritical carbon dioxide with molecular oxygen. Wang X, et al.

Appl. Catal. A Gen. 349(1) , 86-90, (2008)

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