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氧阿苯达唑

氧阿苯达唑用途

Albendazole sulfoxide (Ricobendazole) 是Albendazole 的主要代谢物,具有抗寄生虫活性 (e.g. Echinococcus multilocularis)。

氧阿苯达唑名称

[ CAS 号 ]:
54029-12-8

[ 中文名 ]:
氧阿苯达唑

[ 英文名 ]:
Albendazole Oxide

[中文别名 ]:

[英文别名 ]:

Rycobendazole
MFCD00797922
Albendazole Sulfoxide
Albendazole S-oxide
Ricobendazole
Albendazole sulphoxide
Albendazole oxide

氧阿苯达唑生物活性

[ 描述 ]:

Albendazole sulfoxide (Ricobendazole) 是Albendazole 的主要代谢物,具有抗寄生虫活性 (e.g. Echinococcus multilocularis)。

[ 相关类别 ]:

研究领域 >> 感染

[参考文献]

[1]. Gokhan Adas,, et al. Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study).

氧阿苯达唑物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
357.3ºC at 760 mmHg

[ 熔点 ]:
154-156ºC

[ 分子式 ]:
C₁₂H₁₅N₃O₃S

[ 分子量 ]:
281.331

[ 闪点 ]:
169.9ºC

[ 精确质量 ]:
281.083405

[ PSA ]:
103.29000

[ LogP ]:
0.91

[ 外观性状 ]:
白色至灰白色粉末

[ 折射率 ]:
1.659

[ 储存条件 ]:
-20°C Freezer

氧阿苯达唑安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
22

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
FD1080000

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氧阿苯达唑文献

Azole antifungal inhibition of buprenorphine, methadone and oxycodone in vitro metabolism.

J. Anal. Toxicol. 39 , 374-86, (2015)

Opioid-related mortality rates have escalated. Drug interactions may increase blood concentrations of the opioid. We therefore used human liver microsomes (HLMs) and cDNA-expressed human cytochrome P4...

Validation of a streamlined multiclass, multiresidue method for determination of veterinary drug residues in bovine muscle by liquid chromatography-tandem mass spectrometry.

Anal. Bioanal. Chem 407 , 4423-35, (2015)

Multiclass, multiresidue methods are becoming increasingly popular in regulatory monitoring programs due to their increased analytical scope and laboratory efficiency. In this work, we report the deve...

The transport of albendazole and albendazole sulphoxide in the lancet fluke (Dicrocoelium dendriticum).

Vet. Parasitol. 176(1) , 27-33, (2011)

Albendazole (ABZ) is one of the most important benzimidazole compounds possessing high activity against the lancet fluke, Dicrocoelium dendriticum. ABZ sulphoxide (ABZ.SO) is the main molecule present...

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