<生产厂家价格>

烟酸酰肼

烟酸酰肼用途

烟酸肼是一种小分子化合物[1]。

烟酸酰肼名称

[ CAS 号 ]:
553-53-7

[ 中文名 ]:
3-吡啶甲酰肼

[ 英文名 ]:
Nicotinohydrazide

[中文别名 ]:

[英文别名 ]:

Nicotinohydrazide
pyridine-3-carbohydrazide
EINECS 209-041-0
MFCD00006383
3-Pyridinecarboxylic acid, hydrazide

烟酸酰肼生物活性

[ 描述 ]:

烟酸肼是一种小分子化合物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Kruszynski R. A structural and theoretical study of intermolecular interactions in nicotinohydrazide dihydrochloride. Acta Crystallogr C. 2011 Feb;67(Pt 2):o52-6.

烟酸酰肼物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 熔点 ]:
159-161 °C(lit.)

[ 分子式 ]:
C₆H₇N₃O

[ 分子量 ]:
137.139

[ 精确质量 ]:
137.058914

[ PSA ]:
68.01000

[ LogP ]:
-0.83

[ 折射率 ]:
1.584

[ 储存条件 ]:
2-8°C

烟酸酰肼MSDS

烟酸酰肼毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QT1750000

CHEMICAL NAME :: Nicotinic acid, hydrazide

CAS REGISTRY NUMBER :: 553-53-7

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H7-N3-O

MOLECULAR WEIGHT :: 137.16

WISWESSER LINE NOTATION :: T6NJ CVMZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04178

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,691,1955 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 124 gm/kg/71W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: ONCOBS Oncology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.21- 1967- Volume(issue)/page/year: 38,106,1981

烟酸酰肼安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R40

[ 安全声明 (欧洲) ]:
S22-S26-S36/37/39

[ 危险品运输编码 ]:
UN2811

[ WGK德国 ]:
3

[ RTECS号 ]:
QT1750000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2933399090

烟酸酰肼合成路线

烟酸酰肼上下游产品

烟酸酰肼上游产品

烟酸酰肼下游产品

烟酸酰肼海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

烟酸酰肼文献

Controlled release studies of antimalarial 1, 3, 5-trisubstituted-2-pyrazolines from biocompatible chitosan-heparin Layer-by-Layer (LbL) self assembled thin films.

Colloids Surf. B Biointerfaces 125 , 151-9, (2015)

Herein we report the in-vitro controlled release properties of 1, 3, 5-trisubstituted-2-pyrazolines through Layer-by-Layer (LbL) self assembled thin films fabricated from chitosan and heparin sodium s...

Chemokine CCL17 induced by hypoxia promotes the proliferation of cervical cancer cell.

Am. J. Cancer Res. 5 , 3072-84, (2015)

Cervical cancer is often associated with hypoxia and many kinds of chemokines. But the relationship and role of hypoxia and Chemokine (C-C motif) ligand 17 (CCL17) in cervical cancer are still unknown...

Double-level "orthogonal" dynamic combinatorial libraries on transition metal template.

Proc. Natl. Acad. Sci. U. S. A. 98(4) , 1347-52, (2001)

Dynamic combinatorial libraries are mixtures of compounds that exist in a dynamic equilibrium and can be driven to compositional self adaptation via selective binding of a specific assembly of certain...

更多文献