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丹酰氯

丹酰氯用途

丹磺酰氯是在脂族和芳族胺与伯氨基反应产生稳定蓝色或蓝绿色荧光磺酰胺加合物的一种试剂, 广泛用于修饰氨基酸, 蛋白质测序和氨基酸分析。

丹酰氯名称

[ CAS 号 ]:
605-65-2

[ 中文名 ]:
丹磺酰氯

[ 英文名 ]:
Dansyl chloride

[中文别名 ]:

[英文别名 ]:

5-(Dimethylamino)naphthalene-1-sulfonyl chloride
EINECS 210-092-6
5-(Dimethylamino)-1-naphthalenesulfonyl chloride
MFCD00003985
1-chlorosulfonyl-5-(dimethylamino)naphthalene
Dansyl chloride
1-Naphthalenesulfonyl chloride, 5-(dimethylamino)-

丹酰氯生物活性

[ 描述 ]:

丹磺酰氯是在脂族和芳族胺与伯氨基反应产生稳定蓝色或蓝绿色荧光磺酰胺加合物的一种试剂, 广泛用于修饰氨基酸, 蛋白质测序和氨基酸分析。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

染料试剂

研究领域 >> 其他

[相关活性小分子]

丹酰氯物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
371.3±22.0 °C at 760 mmHg

[ 熔点 ]:
72-74 °C(lit.)

[ 分子式 ]:
C₁₂H₁₂ClNO₂S

[ 分子量 ]:
269.747

[ 闪点 ]:
178.4±22.3 °C

[ 精确质量 ]:
269.027740

[ PSA ]:
45.76000

[ LogP ]:
3.67

[ 外观性状 ]:
黄色细结晶粉末

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.636

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
acetone: 50 mg/mL

丹酰氯MSDS

详细MSDS(安全技术说明书)

丹酰氯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QK3688000

CHEMICAL NAME :: 1-Naphthalenesulfonyl chloride, 5-(dimethylamino)-

CAS REGISTRY NUMBER :: 605-65-2

BEILSTEIN REFERENCE NO. :: 2217205

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H12-Cl-N-O2-S

MOLECULAR WEIGHT :: 269.76

WISWESSER LINE NOTATION :: L66J BSWG GN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00262

丹酰氯安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 3261 8/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
QK3688000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
29214980

丹酰氯上下游产品

丹酰氯上游产品

丹酰氯下游产品

丹酰氯海关

[ 海关编码 ]: 2921199090

[ 中文概述 ]:
2921199090 其他无环单胺及其衍生物及其盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

丹酰氯文献

Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer.

Mol. Pharm. 12(2) , 332-41, (2015)

Polycations are explored as carriers to deliver therapeutic nucleic acids. Polycations are conventionally pharmacological inert with the sole function of delivering therapeutic cargo. This study repor...

The uptake of trehalose glycolipids by macrophages is independent of Mincle.

ChemBioChem. 16(4) , 683-93, (2015)

Trehalose glycolipids play an important role in the pathogenesis of Mycobacterium tuberculosis and are used as adjuvants for vaccines; however, much still remains unanswered about the mechanisms throu...

Sulfur amino acid metabolism in Zucker diabetic fatty rats.

Biochem. Pharmacol. 96 , 256-66, (2015)

The present study was aimed to investigate the metabolomics of sulfur amino acids in Zucker diabetic fatty (ZDF) rats, an obese type 2 diabetic animal model. Plasma levels of total cysteine, homocyste...

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丹酰氯