乙酰丙嗪

乙酰丙嗪名称

[ CAS 号 ]:
61-00-7

[ 中文名 ]:
乙酰丙嗪

[ 英文名 ]:
acepromazine

[英文别名 ]:

Vetranquil
1522CB
Notensil
Acetylperazine
Acetopromazine
Acetylpromazine

乙酰丙嗪物理化学性质

[ 密度 ]:
1.1075 (rough estimate)

[ 沸点 ]:
bp0.5 220-240°

[ 分子式 ]:
C₁₉H₂₂N₂OS

[ 分子量 ]:
326.45600

[ 精确质量 ]:
326.14500

[ PSA ]:
48.85000

[ LogP ]:
4.50860

[ 折射率 ]:
1.5950 (estimate)

[ 储存条件 ]:
库房通风低温干燥

乙酰丙嗪毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OB2275000

CHEMICAL NAME :: Ketone, 10-(3-(dimethylamino)propyl)phenothiazin-2-yl methyl

CAS REGISTRY NUMBER :: 61-00-7

LAST UPDATED :: 199707

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C19-H22-N2-O-S

MOLECULAR WEIGHT :: 326.49

WISWESSER LINE NOTATION :: T C666 BN ISJ B3N1&1 EV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,136,1961

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 113,53,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RMNIBN Revista Medico-Chirurgicala. Medical-Surgical Journal. (Societatea de Medici si Naturalisti, 16 Bulevardul Independentei, Iasi, Romania) V.35- 1924- Volume(issue)/page/year: 81,105,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 130 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 113,53,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 59 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 115,1,1958 *** REVIEWS *** TOXICOLOGY REVIEW JMSCA9 Journal of Mental Science. (London, UK) V.4-108, 1857-1962. For publisher information, see BJPYAJ. Volume(issue)/page/year: 106,755,1960 TOXICOLOGY REVIEW IDPYAK Industrial Pharmacology. (Mount Kisco, NY) V.1-3, 1974-79. Discontinued. Volume(issue)/page/year: 1,203,1974

乙酰丙嗪安全信息

[ 海关编码 ]:
2934300000

乙酰丙嗪上下游产品

乙酰丙嗪上游产品

乙酰丙嗪下游产品

乙酰丙嗪海关

[ 海关编码 ]: 2934300000

[ 中文概述 ]:
2934300000. 含一个吩噻嗪环系的化合物(吩噻嗪环系不论是否氢化,化合物未经进一步稠合的 ). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%