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1-氨基蒽

1-氨基蒽用途

有机合成。

1-氨基蒽名称

[ CAS 号 ]:
610-49-1

[ 中文名 ]:
1-氨基蒽

[ 英文名 ]:
1-Anthracenamine

[中文别名 ]:

[英文别名 ]:

EINECS 210-225-8
MFCD00003579
1-AMINOANTHRACENE

1-氨基蒽物理化学性质

[ 密度 ]:
1.208g/cm3

[ 沸点 ]:
408.2ºC at 760 mmHg

[ 熔点 ]:
114-118 °C(lit.)

[ 分子式 ]:
C₁₄H₁₁N

[ 分子量 ]:
193.24400

[ 闪点 ]:
224.4ºC

[ 精确质量 ]:
193.08900

[ PSA ]:
26.02000

[ LogP ]:
4.15640

[ 外观性状 ]:
固体;Light yellow to Brown to Dark green powder to crystal

[ 折射率 ]:
1.765

[ 储存条件 ]:
库房通风低温干燥

1-氨基蒽MSDS

1-氨基蒽毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CA9100000

CHEMICAL NAME :: 1-Anthracenamine

CAS REGISTRY NUMBER :: 610-49-1

BEILSTEIN REFERENCE NO. :: 2209406

LAST UPDATED :: 199709

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C14-H11-N

MOLECULAR WEIGHT :: 193.26

WISWESSER LINE NOTATION :: L C666J DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7200 mg/kg/27D-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: DNA repair

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 10200 nmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 203,155,1988

1-氨基蒽安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
CA9100000

[ 海关编码 ]:
2921499090

1-氨基蒽合成路线

1-氨基蒽上下游产品

1-氨基蒽上游产品

1-氨基蒽下游产品

1-氨基蒽海关

[ 海关编码 ]: 2921499090

[ 中文概述 ]:
2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

1-氨基蒽文献

Antitumor activity of acriflavine in lung adenocarcinoma cell line A549.

Anticancer Res. 34(11) , 6467-72, (2014)

Aim/Materials and Methods: In order to develop better drugs against non-small cell lung cancer (NSCLC), we screened a variety of compounds and treated the human lung adenocarcinoma cell line A549 with...

Stereoselectivity of isoflurane in adhesion molecule leukocyte function-associated antigen-1.

PLoS ONE 9(5) , e96649, (2014)

Isoflurane in clinical use is a racemate of S- and R-isoflurane. Previous studies have demonstrated that the effects of S-isoflurane on relevant anesthetic targets might be modestly stronger (less tha...

Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines.

Eur. J. Med. Chem. 42 , 1396-402, (2007)

Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry...

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