CB-002
更新时间：2024-07-20 12:55:48
CB-002结构式
|
常用名 | CB-002 | 英文名 | CB-002 |
|---|---|---|---|---|
| CAS号 | 61034-15-9 | 分子量 | 271.27500 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C13H13N5O2 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
CB-002用途CB-002 is a novel small molecule that restores p53 function in mutant p53-expressing colorectal cancer cells without toxicity to normal human fibroblasts; increases expression of endogenous p53 target genes NOXA, DR5, and p21 and cell death; decreases the stability of mutant p53 in RXF393 cancer cells and an exogenously expressed R175H p53 mutant in HCT116 p53-null cells. |
| 英文名 | 8-anilino-1,3-dimethyl-7H-purine-2,6-dione |
|---|---|
| 英文别名 | 更多 |
| 分子式 | C13H13N5O2 |
|---|---|
| 分子量 | 271.27500 |
| 精确质量 | 271.10700 |
| PSA | 87.94000 |
| LogP | 0.12580 |
| 8-Anilino-1,3-dimethyl-3,7-dihydro-purin-2,6-dion |
| 8-Phenylaminotheophyllin |
| 8-anilino-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione |
| 8-Anilino-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione |
| 8-phenylaminotheophylline |
| 8-anilino-1,3-dimethyl-3,7-dihydro-purine-2,6-dione |
| 1H-purine-2,6-dione,3,7-dihydro-1,3-dimethyl-8-(phenylamino) |
| 8-anilino-1,3-dimethyl-3,7(9)-dihydro-purine-2,6-dione |
