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奎宁盐酸盐二水合物

奎宁盐酸盐二水合物用途

Quinine盐酸盐二水合物具有退热,抗疟,止痛,抗炎等特性。

奎宁盐酸盐二水合物名称

[ CAS 号 ]:
6119-47-7

[ 中文名 ]:
奎宁单盐酸盐二水合物

[ 英文名 ]:
Quinine Hydrochloride Dihydrate

[中文别名 ]:

[英文别名 ]:

EINECS 231-437-7
MFCD00151248
Quinine monohydrochloride dihydrate
Quinine Hydrochloride Dihydrate
Quinine (hydrochloride dihydrate)

奎宁盐酸盐二水合物生物活性

[ 描述 ]:

Quinine盐酸盐二水合物具有退热,抗疟,止痛,抗炎等特性。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 寄生物

研究领域 >> 感染

[参考文献]

[1]. White, N.J., et al., Quinine pharmacokinetics and toxicity in cerebral and uncomplicated Falciparum malaria. Am J Med, 1982. 73(4): p. 564-72.

[相关活性小分子]

奎宁盐酸盐二水合物物理化学性质

[ 沸点 ]:
633ºC at 760 mmHg

[ 熔点 ]:
115-116 °C (dec.)(lit.)

[ 分子式 ]:
C₂₀H₂₉ClN₂O₄

[ 分子量 ]:
396.908

[ 闪点 ]:
122 °C

[ 精确质量 ]:
396.181580

[ PSA ]:
64.05000

[ LogP ]:
3.78450

[ 外观性状 ]:
白色至淡黄色晶体粉末

[ 折射率 ]:
-250 ° (C=2, EtOH)

[ 储存条件 ]:
Store at -20°C

奎宁盐酸盐二水合物MSDS

详细MSDS(安全技术说明书)

奎宁盐酸盐二水合物安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H317-H334

[ 警示性声明 ]:
P261-P280-P342 + P311

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22;R36/37/38

[ 安全声明 (欧洲) ]:
S22-S36/37-S45-S36/37/39-S26

[ 危险品运输编码 ]:
1544

[ WGK德国 ]:
3

[ RTECS号 ]:
VA7700000

[ 海关编码 ]:
29392000

奎宁盐酸盐二水合物上下游产品

奎宁盐酸盐二水合物上游产品

奎宁盐酸盐二水合物下游产品

奎宁盐酸盐二水合物海关

[ 海关编码 ]: 29392000

奎宁盐酸盐二水合物文献

Photostability profiles of the experimental antimetastatic ruthenium complex NAMI-A.

J. Pharm. Biomed. Anal. 30(4) , 1287-96, (2002)

NAMI-A is a novel ruthenium complex with selective activity against metastases currently in Phase I clinical trials in The Netherlands. The photostability of this new agent in solid state and in solut...

Quinine blocks a calcium-activated potassium conductance in mammalian enteric neurones.

Br. J. Pharmacol. 83(1) , 3-5, (1984)

Quinine (100 microM) abolished the slow calcium-dependent afterhyperpolarization which occurs after an action potential in some neurones of the guinea-pig myenteric and submucous plexus. This occurred...

Treatment of severe malaria.

J. R. Soc. Med. 82 Suppl 17 , 44-50; discussion 50-1, (1989)

In the treatment of severe Plasmodium falciparum infection antimalarial drugs should, ideally, be given by controlled rate intravenous infusion until the patient is able to swallow tablets. In cases w...

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