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N,N'-二乙酰联苯胺

N,N'-二乙酰联苯胺名称

[ CAS 号 ]:
613-35-4

[ 中文名 ]:
N,N'-二乙酰联苯胺

[ 英文名 ]:
N,N'-DIACETYLBENZIDINE

[中文别名 ]:

N,N’-醋酸联苯胺

[英文别名 ]:

Acetamide, N,N'-[1,1'-biphenyl]-4,4'-diylbis-
N-[4'-(acetylamino)[1,1'-biphenyl]-4-yl]acetamide
N-[4-(4-acetamidophenyl)phenyl]acetamide
EINECS 210-338-2
N,N'-biphenyl-4,4'-diyldiacetamide
N,N'-DIACETYLBENZIDINE
N,N'-4,4'-Biphenyldiyldiacetamide

N,N'-二乙酰联苯胺物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
562.9±43.0 °C at 760 mmHg

[ 熔点 ]:
328.3ºC

[ 分子式 ]:
C₁₆H₁₆N₂O₂

[ 分子量 ]:
268.310

[ 闪点 ]:
224.7±28.3 °C

[ 精确质量 ]:
268.121185

[ PSA ]:
58.20000

[ LogP ]:
2.31

[ 外观性状 ]:
米白色至浅紫色固体

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.638

[ 储存条件 ]:
通风低温干燥

N,N'-二乙酰联苯胺MSDS

详细MSDS(安全技术说明书)

N,N'-二乙酰联苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DT2800000

CHEMICAL NAME :: 4',4'''-Biacetanilide

CAS REGISTRY NUMBER :: 613-35-4

BEILSTEIN REFERENCE NO. :: 2217711

LAST UPDATED :: 199709

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C16-H16-N2-O2

MOLECULAR WEIGHT :: 268.34

WISWESSER LINE NOTATION :: 1VMR DR DMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6300 mg/kg/35W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 64 mg/kg/4W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Endocrine - tumors Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - changes in both tubules and glomeruli

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4350 mg/kg/39W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - changes in both tubules and glomeruli

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 389,3,1997 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,293,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,293,1978 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FRANCE;Carcinogen JAN 1993

N,N'-二乙酰联苯胺安全信息

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
20/21/22

[ 安全声明 (欧洲) ]:
S22;S26

[ RTECS号 ]:
DT2800000

[ 海关编码 ]:
2924299090

N,N'-二乙酰联苯胺合成路线

详细合成路线

N,N'-二乙酰联苯胺上下游产品

N,N'-二乙酰联苯胺上游产品

N,N'-二乙酰联苯胺下游产品

N,N'-二乙酰联苯胺海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%