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2-氯-4-硝基酚

2-氯-4-硝基酚用途

【用途一】
用于有机合成
【用途二】
有机合成中间体。

2-氯-4-硝基酚名称

[ CAS 号 ]:
619-08-9

[ 中文名 ]:
2-氯-4-硝基苯酚

[ 英文名 ]:
2-Chloro-4-nitrophenol

[中文别名 ]:

[英文别名 ]:

2-Chloro-4-nitrophenol
Phenol, 2-chloro-4-nitro-
3-Carboxybenzaldehyde
EINECS 210-578-8
MFCD00043910
2-Chlor-4-nitrobenzolol

2-氯-4-硝基酚物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
290.6±25.0 °C at 760 mmHg

[ 熔点 ]:
106 °C

[ 分子式 ]:
C₆H₄ClNO₃

[ 分子量 ]:
173.554

[ 闪点 ]:
129.6±23.2 °C

[ 精确质量 ]:
172.987976

[ PSA ]:
66.05000

[ LogP ]:
2.22

[ 外观性状 ]:
白色粉末或针状形态结晶

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.627

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

[ 水溶解性 ]:
slightly soluble

2-氯-4-硝基酚MSDS

2-氯-4-硝基酚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SK5075000

CHEMICAL NAME :: Phenol, 2-chloro-4-nitro-

CAS REGISTRY NUMBER :: 619-08-9

BEILSTEIN REFERENCE NO. :: 2046372

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H4-Cl-N-O3

MOLECULAR WEIGHT :: 173.56

WISWESSER LINE NOTATION :: WNR DQ CG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570573

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,868,1975

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570573

2-氯-4-硝基酚安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H312-H315-H319-H332-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ 危险品运输编码 ]:
2811

[ WGK德国 ]:
3

[ RTECS号 ]:
SK5075000

[ 海关编码 ]:
29089000

2-氯-4-硝基酚合成路线

2-氯-4-硝基酚上下游产品

2-氯-4-硝基酚上游产品

2-氯-4-硝基酚下游产品

2-氯-4-硝基酚制备

由对硝基酚经氯化而得。将对硝基酚和浓盐酸混合，加热溶解。冷却后慢慢加入氯酸钾水溶液，加毕搅拌半小时，放置过夜，过滤，用水洗去酸性即得粗品。粗品用80-90℃热水及少许乙酸溶解，脱色过滤，冷却，析出针状结晶即为成品。

2-氯-4-硝基酚海关

[ 海关编码 ]: 2908999090

[ 中文概述 ]:
2908999090 其他酚及酚醇的卤化等衍生物（包括其磺化、硝化或亚硝化衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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