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盐酸肾上腺酮

盐酸肾上腺酮用途

Adrenalone盐酸盐是一种选择性的α1肾上腺素受体激动剂,用作局部血管收缩剂和止血剂,用于延长局部麻醉剂的作用。

盐酸肾上腺酮名称

[ CAS 号 ]:
62-13-5

[ 中文名 ]:
盐酸肾上腺酮

[ 英文名 ]:
Adrenalone hydrochloride

[中文别名 ]:

[英文别名 ]:

Adrenalonium chloratum
ADRENALONE,HYDROCHLORIDE
Epinephrine ketone hydrochloride
MFCD00035075
Adrenalone HCL
Stryphnonasal
Adrenone hydrochloride
adrenalon hydrochloride
EINECS 200-525-7
Kephrine hydrochloride

盐酸肾上腺酮生物活性

[ 描述 ]:

Adrenalone盐酸盐是一种选择性的α1肾上腺素受体激动剂,用作局部血管收缩剂和止血剂,用于延长局部麻醉剂的作用。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体

研究领域 >> 其他

[相关活性小分子]

盐酸肾上腺酮物理化学性质

[ 沸点 ]:
405.6ºC at 760 mmHg

[ 熔点 ]:
244-249 °C (dec.)

[ 分子式 ]:
C₉H₁₂ClNO₃

[ 分子量 ]:
217.650

[ 精确质量 ]:
217.050568

[ PSA ]:
69.56000

[ LogP ]:
1.69280

[ 外观性状 ]:
棕色灰色固体

[ 储存条件 ]:
2-8°C

盐酸肾上腺酮MSDS

详细MSDS(安全技术说明书)

盐酸肾上腺酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AM8225000

CHEMICAL NAME :: Acetophenone, 3',4'-dihydroxy-2-(methylamino)-, hydrochloride

CAS REGISTRY NUMBER :: 62-13-5

LAST UPDATED :: 199009

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C9-H11-N-O3.Cl-H

MOLECULAR WEIGHT :: 217.67

WISWESSER LINE NOTATION :: QR BQ DV1M1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 71,62,1941

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 902 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 92,369,1948

盐酸肾上腺酮安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
AM8225000

[ 海关编码 ]:
2922509090

盐酸肾上腺酮海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

盐酸肾上腺酮文献

[Radiation protective effect of beta-ketoanalogs of hydroxyphenyl ethanolamines].

Radiats. Biol. Radioecol. 37(6) , 914-7, (1997)

Experiments are carried out on 3400 mice, irradiated in dose 8 Gy (LD97/30). beta-Ketoanalogs of adrenaline (adrenalone, 50-150 mumol/kg), m,p-dipivaloyladrenaline (20 mumol/kg) and phenylephrine (but...

Electron spin resonance-spin stabilization of semiquinones produced during oxidation of epinephrine and its analogues.

J. Biol. Chem. 259(1) , 354-8, (1984)

The ESR-spin stabilization approach has been employed to detect and characterize o-semiquinone radicals from the oxidation of epinephrine and related materials (norepinephrine, 3,4-dihydroxynorephedri...

Formation of adrenaline in the iris-ciliary body from adrenalone diesters.

Exp. Eye Res. 38(6) , 621-6, (1984)

Many diesters of adrenalone have high ocular sympathomimetic activity although adrenalone itself, even if delivered intraocularly, is practically inactive. Thus these diesters cannot be considered pro...

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