1-methyl-7-pentoxy-9H-pyrido[3,4-b]indole,hydrochloride
名称
[ CAS 号 ]:
63885-68-7
[ 英文名 ]:
1-methyl-7-pentoxy-9H-pyrido[3,4-b]indole,hydrochloride
[英文别名 ]:
- Amyl harmol hydrochloride
- O-n-Amyl harmol hydrochloride
物理化学性质
[ 沸点 ]:
457ºC at 760mmHg
[ 分子式 ]:
C17H21ClN2O
[ 分子量 ]:
304.81400
[ 闪点 ]:
149.9ºC
[ 精确质量 ]:
304.13400
[ PSA ]:
37.91000
[ LogP ]:
5.39550
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UV0361500
- CHEMICAL NAME :
- 9H-Pyrido(3,4-b)indole, 1-methyl-7-pentyloxy-, hydrochloride
- CAS REGISTRY NUMBER :
- 63885-68-7
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C17-H20-N2-O.Cl-H
- MOLECULAR WEIGHT :
- 304.85
- WISWESSER LINE NOTATION :
- T B656 EN HMJ F1 KO5 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 5,56,1932
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 5,56,1932
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - ataxia Nutritional and Gross Metabolic - body temperature increase
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 5,56,1932
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