<生产厂家价格>

Destruxin A

Destruxin A用途

Destruxin A(DA)是来源昆虫病原真菌 Metarhizium anisopliae 的环肽霉菌毒素,具有杀虫、抗病毒和抗增殖活性。

Destruxin A名称

[ CAS 号 ]:
6686-70-0

[ 中文名 ]:
绿僵菌素A

[ 英文名 ]:
Destruxin A

[英文别名 ]:

Destruxin A from Metarrhizium anisopliae

Destruxin A生物活性

[ 描述 ]:

Destruxin A(DA)是来源昆虫病原真菌 Metarhizium anisopliae 的环肽霉菌毒素,具有杀虫、抗病毒和抗增殖活性。

[ 相关类别 ]:

研究领域 >> 癌症

研究领域 >> 感染

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Gong L, et al. Gene expression profile of Bombyx mori hemocyte under the stress of destruxin A. PLoS One. 2014 May 6;9(5):e96170.

[2]. Pal S, et al. Fungal peptide Destruxin A plays a specific role in suppressing the innate immune response in Drosophila melanogaster. J Biol Chem. 2007 Mar 23;282(12):8969-77.

[3]. Odier F, et al. In vitro effect of fungal cyclodepsipeptides on leukemic cells: study of destruxins A, B and E. Biol Cell. 1992;74(3):267-71.

Destruxin A物理化学性质

[ 分子式 ]:
C₂₉H₄₇N₅O₇

[ 分子量 ]:
577.71300

[ 精确质量 ]:
577.34800

[ PSA ]:
152.41000

[ LogP ]:
1.21150

[ 储存条件 ]:
-20°C

Destruxin AMSDS

详细MSDS(安全技术说明书)

Destruxin A安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H312-H315-H319-H332-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 风险声明 (欧洲) ]:
20/21/22-36/37/38-48

[ 安全声明 (欧洲) ]:
26-36-45

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
HH1500000

Destruxin A文献

Concurrence of losing a chromosome and the ability to produce destruxins in a mutant of Metarhizium anisopliae.

FEMS Microbiol. Lett. 226(2) , 373-8, (2003)

In a previous study, a spontaneous subtilisin pr1A and pr1B gene-deficient mutant of the entomopathogenic fungus Metarhizium anisopliae strain V275 has been identified [Wang, C.-S. et al. (2002) FEMS ...

Synthesis and biological evaluation of destruxin A and related analogs.

J. Pept. Res. 58(1) , 1-11, (2001)

This report describes the development of an efficient solid-phase synthesis protocol and adaptation of reported solution phase procedures for the synthesis of the cyclic depsihexapeptide destruxin A a...

Non-cyclic AMP-dependent, positive inotropic cyclodepsipeptides with negative chronotropy.

J. Pharmacol. Exp. Ther. 290(3) , 1006-12, (1999)

The effects of natural cyclodepsipeptides (CDPs) on isolated rat cardiac tissue preparations were examined in vitro. Destruxin A, destruxin B (DB), roseotoxin B (RB), and roseocardin (RC), a novel CDP...

更多文献