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β-氯曲沙明二盐酸盐

β-氯曲沙明二盐酸盐名称

[ CAS 号 ]:
67025-98-3

[ 中文名 ]:
β-氯曲沙明二盐酸盐

[ 英文名 ]:
BETA-CHLORNALTREXAMINE 2HCL

[英文别名 ]:

C24H32Cl2N2O3.2HCl
|A-Chlornaltrexamine dihydrochloride
|A-CNA
chlornaltrexamine hydrochloride
Chlornaltrexamine dihydrochloride

β-氯曲沙明二盐酸盐物理化学性质

[ 分子式 ]:
C₂₄H₃₄Cl₄N₂O₃

[ 分子量 ]:
540.35000

[ 精确质量 ]:
538.13200

[ PSA ]:
56.17000

[ LogP ]:
4.64640

β-氯曲沙明二盐酸盐MSDS

详细MSDS(安全技术说明书)

β-氯曲沙明二盐酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
QC7792000

β-氯曲沙明二盐酸盐文献

Methocinnamox is a potent, long-lasting, and selective antagonist of morphine-mediated antinociception in the mouse: comparison with clocinnamox, beta-funaltrexamine, and beta-chlornaltrexamine.

J. Pharmacol. Exp. Ther. 294 , 933, (2000)

The irreversible mu-opioid antagonists beta-funaltrexamine (beta-FNA) and beta-chlornaltrexamine (beta-CNA) are important pharmacological tools but have a kappa-agonist activity and, in the latter cas...

Relationship between kappa 1 opioid receptor binding and inhibition of adenylyl cyclase in guinea pig brain membranes.

Biochem. Pharmacol. 45(1) , 207-16, (1993)

Previously, we showed that kappa-selective ligands inhibit adenylyl cyclase in guinea pig cerebellar membranes. The present studies explore the relationship between kappa 1 binding sites (as determine...

Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding.

J. Biol. Chem. 276(37) , 34624-30, (2001)

The mu opioid receptor (MOR) plays a central role in mediating acute and chronic effects of narcotic drugs. Three rare single nucleotide polymorphisms in the hMOR gene have been identified that cause ...

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