2-氨基二吡啶并[1,2-A:3’,2’-D]咪唑盐酸盐
名称
[ CAS 号 ]:
67730-10-3
[ 中文名 ]:
2-氨基二吡啶并[1,2-A:3’,2’-D]咪唑盐酸盐
[ 英文名 ]:
2-AMINODIPYRIDO[1,2-A:3',2-D]IMIDAZOLE, HYDROCHLORIDE
[中文别名 ]:
物理化学性质
[ 密度 ]:
1.47 g/cm3
[ 沸点 ]:
349.7ºC at 760 mmHg
[ 熔点 ]:
300ºC
[ 分子式 ]:
C10H9ClN4
[ 分子量 ]:
220.65800
[ 闪点 ]:
165.3ºC
[ 精确质量 ]:
220.05200
[ PSA ]:
56.21000
[ LogP ]:
2.84790
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JM5615000
- CAS REGISTRY NUMBER :
- 67730-10-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 18
- MOLECULAR FORMULA :
- C10-H8-N4
- MOLECULAR WEIGHT :
- 184.22
- WISWESSER LINE NOTATION :
- T B656 AN CN HNJ DZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12500 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Reproductive - Tumorigenic effects - other reproductive system tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 23100 mg/kg/83W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 24024 mg/kg/66W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 23232 mg/kg/69W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 13 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Liver - tumors
- TYPE OF TEST :
- DNA damage
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- BBRCA9 Biochemical and Biophysical Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 96,611,1980 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,235,1986 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,235,1986 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
安全信息
[ 危害码 (欧洲) ]:
Xi
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标题：67730-10-3_CAS号:67730-10-3_2-氨基二吡啶并[1,2-A:3’,2’-D]咪唑盐酸盐 - 化源网 地址：https://www.chemsrc.com/amp/cas/67730-10-3_27841.html