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Palmitoylcarnitine chloride

Palmitoylcarnitine chloride用途

Palmitoylcarnitine chloride 是一种脂肪酸衍生的线粒体底物,通过影响促炎途径,Ca2+ 流入和 DHT 样作用,可选择性降低大肠和前列腺癌细胞的细胞存活率。

Palmitoylcarnitine chloride名称

[ CAS 号 ]:
6865-14-1

[ 中文名 ]:
(±)-棕榈酰肉碱氯化物

[ 英文名 ]:
UNII:EIL57224QR

[英文别名 ]:

Palmitoyl-L-carnitine chloride
UNII:EIL57224QR
(±)-Palmitoylcarnitine chloride

Palmitoylcarnitine chloride生物活性

[ 描述 ]:

Palmitoylcarnitine chloride 是一种脂肪酸衍生的线粒体底物,通过影响促炎途径,Ca2+ 流入和 DHT 样作用,可选择性降低大肠和前列腺癌细胞的细胞存活率。

[ 相关类别 ]:

研究领域 >> 癌症

研究领域 >> 炎症/免疫

[参考文献]

[1]. Al-Bakheit A, et al. Accumulation of Palmitoylcarnitine and Its Effect on Pro-Inflammatory Pathways and Calcium Influx in Prostate Cancer. Prostate. 2016 Oct;76(14):1326-37.

Palmitoylcarnitine chloride物理化学性质

[ 分子式 ]:
C₂₃H₄₆ClNO₄

[ 分子量 ]:
436.069

[ 精确质量 ]:
435.311523

[ PSA ]:
63.60000

[ LogP ]:
2.56440

[ 外观性状 ]:
粉末

[ 储存条件 ]:
20°C

Palmitoylcarnitine chlorideMSDS

Palmitoylcarnitine chloride安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2923900090

Palmitoylcarnitine chloride合成路线

Palmitoylcarnitine chloride上下游产品

Palmitoylcarnitine chloride上游产品

Palmitoylcarnitine chloride下游产品

Palmitoylcarnitine chloride海关

[ 海关编码 ]: 2923900090

[ 中文概述 ]:
2923900090 其他季铵盐及季铵碱。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Palmitoylcarnitine chloride文献

Modulation by palmitoylcarnitine of protein kinase C activation.

Cancer Res. 47 , 6537-6542, (1987)

Palmitoylcarnitine, a reported protein kinase C inhibitor, enhanced the phorbol ester dependency of the enzyme, augmenting protein kinase C activity in the presence of phorbol esters such as phorbol 1...

Palmitoyl-DL-carnitine has calcium-dependent effects on cultured neurones from rat dorsal root ganglia.

Br. J. Pharmacol. 107 , 1192-1197, (1992)

1. The effects of palmitoyl-DL-carnitine (0.01 to 1 mM) on whole cell voltage-activated calcium channel currents carried by calcium or barium and Ca(2+)-activated chloride currents were studied in cul...

Palmitoyl-L-carnitine modifies the function of vascular endothelium.

Cardiovasc. Res. 28 , 129-134, (1994)

Palmitoyl-L-carnitine, which accumulates in ischaemic myocardium, may influence the function of vascular endothelium in the ischaemic area. The aim of the study was therefore to examine the effect of ...

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