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二硫赤藓醇(DTE)

二硫赤藓醇(DTE)名称

[ CAS 号 ]:
6892-68-8

[ 中文名 ]:
1,4-二硫代赤藓醇

[ 英文名 ]:
Dithioerythritol

[中文别名 ]:

[英文别名 ]:

DITHIOERYTHRITOL
DL-1,4-Dithiothreitol
DTT
MFCD00063750
1,4-Dithiothreitol
1,4-Bissulfanylbutane-2,3-diol
DL-1,4-Dimercapto-2,3-dihydroxybutane
2,3-Butanediol, 1,4-dimercapto-, (2S,3S)-
THREO-2,3-DIHYDROXY-1,4-DITHIOLBUTANE
Erythritol, 1,4-dithio-

二硫赤藓醇(DTE)生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

[参考文献]

[1]. Dithioerythritol, From Wikipedia

[相关活性小分子]

二硫赤藓醇(DTE)物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
364.5±42.0 °C at 760 mmHg

[ 熔点 ]:
82-86ºC

[ 分子式 ]:
C₄H₁₀O₂S₂

[ 分子量 ]:
154.251

[ 闪点 ]:
174.2±27.9 °C

[ 精确质量 ]:
154.012222

[ PSA ]:
118.06000

[ LogP ]:
0.07

[ 外观性状 ]:
白色固体

[ 蒸汽压 ]:
0.0±1.8 mmHg at 25°C

[ 折射率 ]:
1.579

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
H2O: 10 mg/mL, clear, colorless | Soluble

二硫赤藓醇(DTE)MSDS

详细MSDS(安全技术说明书)

二硫赤藓醇(DTE)毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KF2410000

CHEMICAL NAME :: Erythritol, 1,4-dithio-

CAS REGISTRY NUMBER :: 6892-68-8

BEILSTEIN REFERENCE NO. :: 1719756

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C4-H10-O2-S2

MOLECULAR WEIGHT :: 154.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 309 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 100 umol/L

REFERENCE :: HEREAY Hereditas (Lund, Sweden). (Gjoerloffsgatan 121, S-261 34 Landskrona, Sweden) V.1- 1947- Volume(issue)/page/year: 91,105,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4164 No. of Facilities: 315 (estimated) No. of Industries: 2 No. of Occupations: 4 No. of Employees: 8177 (estimated) No. of Female Employees: 5997 (estimated)

二硫赤藓醇(DTE)安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39

[ 危险品运输编码 ]:
UN 3335

[ WGK德国 ]:
3

[ RTECS号 ]:
KF2410000

[ 海关编码 ]:
29309070

二硫赤藓醇(DTE)合成路线

详细合成路线

二硫赤藓醇(DTE)上下游产品

二硫赤藓醇(DTE)上游产品

二硫赤藓醇(DTE)下游产品

二硫赤藓醇(DTE)海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

二硫赤藓醇(DTE)文献

Heterotrimeric NADH-oxidizing methylenetetrahydrofolate reductase from the acetogenic bacterium Acetobacterium woodii.

J. Bacteriol. 197(9) , 1681-9, (2015)

The methylenetetrahydrofolate reductase (MTHFR) of acetogenic bacteria catalyzes the reduction of methylene-THF, which is highly exergonic with NADH as the reductant. Therefore, the enzyme was suggest...

Markers of mesterolone abuse in sulfate fraction for doping control in human urine.

J. Mass Spectrom. 50 , 1409-19, (2015)

This manuscript describes the direct detection of mesteroloe sulfo-conjugated metabolites by liquid chromatography/quadrupole/time of flight mass spectrometry (LC/Q/TOFMS) with special focus on evalua...

Proteomic analysis of the cytotoxic effects induced by the organogold(III) complex Aubipyc in cisplatin-resistant A2780 ovarian cancer cells: further evidence for the glycolytic pathway implication.

Mol. Biosyst. 11 , 1653-67, (2015)

The cellular alterations produced in cisplatin-resistant A2780 ovarian cancer cells (A2780/R) upon treatment with the cytotoxic organogold(III) complex Aubipyc were investigated in depth through a cla...

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