非阿尿苷
非阿尿苷用途
非阿尿苷名称
[ CAS 号 ]:
69123-98-4
[ 中文名 ]:
非阿尿苷
[ 英文名 ]:
Fialuridine
[中文别名 ]:
[英文别名 ]:
- Fialuridine
- 5-Iodo-2'-fluoroarauracil
- 2'-Deoxy-2'-fluoro-5-iodouridine
非阿尿苷生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
非阿尿苷物理化学性质
[ 密度 ]:
2.2±0.1 g/cm3
[ 熔点 ]:
216-217ºC
[ 分子式 ]:
C9H10FIN2O5
[ 分子量 ]:
372.09
[ 精确质量 ]:
371.961823
[ PSA ]:
104.55000
[ LogP ]:
-0.32
[ 外观性状 ]:
无色晶体
[ 折射率 ]:
1.685
[ 储存条件 ]:
Refrigerator
[ 水溶解性 ]:
DMSO: soluble5mg/mL, clear (warmed)
非阿尿苷MSDS
非阿尿苷毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YQ9512500
- CHEMICAL NAME :
- Uracil, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodo-
- CAS REGISTRY NUMBER :
- 69123-98-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H10-F-I-N2-O5
- MOLECULAR WEIGHT :
- 372.11
- WISWESSER LINE NOTATION :
- T6NVMVJ EI A- BT5OTJ CF DQ E1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 9100 ug/kg/13W-I
- TOXIC EFFECTS :
- Liver - jaundice, other or unclassified Liver - liver function tests impaired Nutritional and Gross Metabolic - metabolic acidosis
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 40 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,3957,1982
非阿尿苷安全信息
[ 危害码 (欧洲) ]:
Xi
[ 安全声明 (欧洲) ]:
24/25
[ 危险品运输编码 ]:
NONH for all modes of transport
[ RTECS号 ]:
YQ9512500
[ 海关编码 ]:
2934999090
非阿尿苷合成路线
非阿尿苷上下游产品
非阿尿苷上游产品
非阿尿苷下游产品
非阿尿苷海关
[ 海关编码 ]: 2934999090
[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
非阿尿苷文献
Nucl. Med. Biol. 37(4) , 439-42, (2010)
An improved synthesis of 2'-[(18)F]-fluoro-2'-deoxy-1-beta-D-arabinofuranosyl-5-iodouracil ([(18)F]-FIAU) has been developed. The method utilizes trimethylsilyl trifluoromethanesulfonate (TMSOTf) cata...
Imaging of a localized bacterial infection with endogenous thymidine kinase using radioisotope-labeled nucleosides.Int. J. Med. Microbiol. 302(2) , 101-7, (2012)
The importance of noninvasive imaging methods to bacterial infections is widely recognized. To obtain bacterial infection imaging with radioisotope-labeled nucleosides, bacterial thymidine kinase (tk)...
Enhanced antitumor effects by combination gene therapy using MDR1 gene shRNA and HSV1-tk in a xenograft mouse model.Cancer Lett. 291(1) , 83-9, (2010)
The use of a novel therapeutic vector containing HSV1-thymidine kinase (HSV1-tk) and a short hairpin RNA for the MDR1 gene (shMDR) was proposed previously. We investigated the antitumor effects in an ...
推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
产品详情:1-(2-脱氧-2-氟-β-D-阿拉伯呋喃基)-5-碘尿嘧啶
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥3928.0/25mg
¥988.0/5mg
联系人:刘佳
产品详情:1-(2-脱氧-2-氟-β-D-阿拉伯呋喃基)-5-碘尿嘧啶
公司名:上海源溪生物科技有限公司
区域:上海市浦东新区
价格:
¥需询单/1g
联系人:赖经理
产品详情:Fialuridine
公司名:上海脉铂医药科技有限公司
区域:上海市嘉定区
价格:
¥3733.0/25mg
¥1744.0/10mg
¥964.0/5mg
¥需询单/1g
联系人:李先生
产品详情:Fialuridine
公司名:上海创赛科技有限公司
区域:上海市嘉定区
价格:
¥3669.12/25mg
¥1719.9/10mg
¥955.5/5mg
联系人:夏言
产品详情:Fialuridine
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相关化合物
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标题:非阿尿苷_MSDS_用途_密度_非阿尿苷CAS号【69123-98-4】_化源网 地址:https://www.chemsrc.com/amp/cas/69123-98-4_830485.html