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Nε-乙酰基-L-赖氨酸

Nε-乙酰基-L-赖氨酸用途

Nepsilon-Acetyl-L-lysine是氨基酸赖氨酸的衍生物。

Nε-乙酰基-L-赖氨酸名称

[ CAS 号 ]:
692-04-6

[ 中文名 ]:
N-EPSILON-乙酰-L-赖胺基乙酸

[ 英文名 ]:
N6-acetyl-L-lysine

[中文别名 ]:

[英文别名 ]:

Ne-Acetyl-L-lysine
Ne-Acetyllysine
MFCD00002639
N-ε-ACETYL-L-LYSINE
L-Lysine, N-acetyl-
N(6)-acetyl-L-lysine
(S)-6-Acetamido-2-aminohexanoic acid
L-Lysine, N-(1-hydroxyethylidene)-, (Z)-
N-Acetyl-L-lysine
(Z)-N-(1-Hydroxyethylidene)-L-lysine

Nε-乙酰基-L-赖氨酸生物活性

[ 描述 ]:

Nepsilon-Acetyl-L-lysine是氨基酸赖氨酸的衍生物。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Schmidt H, et al. Characterization of a novel enzyme, N6-acetyl-L-lysine: 2-oxoglutarate aminotransferase, which catalyses the second step of lysine catabolism in Candida maltosa. Antonie Van Leeuwenhoek. 1992 Nov;62(4):285-90.

[相关活性小分子]

Nε-乙酰基-L-赖氨酸物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
442.0±40.0 °C at 760 mmHg

[ 熔点 ]:
250 °C (dec.)(lit.)

[ 分子式 ]:
C₈H₁₆N₂O₃

[ 分子量 ]:
188.224

[ 闪点 ]:
221.1±27.3 °C

[ 精确质量 ]:
188.116089

[ PSA ]:
92.42000

[ LogP ]:
-1.42

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 蒸汽压 ]:
0.0±2.3 mmHg at 25°C

[ 折射率 ]:
1.490

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
水溶性：微溶

Nε-乙酰基-L-赖氨酸MSDS

Nε-乙酰基-L-赖氨酸安全信息

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
29241900

Nε-乙酰基-L-赖氨酸合成路线

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Nε-乙酰基-L-赖氨酸文献

Hypernuclear acetylation in atherosclerotic lesions and activated vascular smooth muscle cells.

Biochem. Biophys. Res. Commun. 266(2) , 417-24, (1999)

Recent studies have implicated acetylation of several nuclear proteins such as histones and p53 on their epsilon-portion of lysine residues in eukaryotic transcription. Here we raised a specific polyc...

Proteomic analysis of organ-specific post-translational lysine-acetylation and -methylation in mice by use of anti-acetyllysine and -methyllysine mouse monoclonal antibodies.

Proteomics 5(18) , 4653-64, (2005)

Post-translational lysine-acetylation and -methylation are two major PTMs of lysine residues in proteins. Recently, we established pan-reactive anti-acetyllysine mouse mAbs, which can bind to Nepsilon...

Purification and characterization of a novel aminoacylase from Streptomyces mobaraensis.

Biosci. Biotechnol. Biochem. 69 , 1914-1922, (2005)

A novel aminoacylase was purified to homogeneity from culture broth of Streptomyces mobaraensis, as evidenced by SDS-polyacrylamide gel electrophoresis (PAGE). The enzyme was a monomer with an approxi...

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