Urea, (diphenylmethyl)- (8CI)(9CI)
Urea, (diphenylmethyl)- (8CI)(9CI)名称
[ CAS 号 ]:
724-18-5
[ 英文名 ]:
Urea, (diphenylmethyl)- (8CI)(9CI)
[英文别名 ]:
- Urea,1-diphenylmethyl
- Benzhydryl-harnstoff
Urea, (diphenylmethyl)- (8CI)(9CI)物理化学性质
[ 密度 ]:
1.156g/cm3
[ 沸点 ]:
389.7ºC at 760 mmHg
[ 分子式 ]:
C14H14N2O
[ 分子量 ]:
226.27400
[ 闪点 ]:
189.5ºC
[ 精确质量 ]:
226.11100
[ PSA ]:
55.12000
[ LogP ]:
3.53550
[ 折射率 ]:
1.604
Urea, (diphenylmethyl)- (8CI)(9CI)毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YT2000000
- CHEMICAL NAME :
- Urea, 1-diphenylmethyl-
- CAS REGISTRY NUMBER :
- 724-18-5
- BEILSTEIN REFERENCE NO. :
- 2807619
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C14-H14-N2-O
- MOLECULAR WEIGHT :
- 226.30
- WISWESSER LINE NOTATION :
- ZVM1R DR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,355,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,355,1976 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 45500 mg/kg/13W-I
- TOXIC EFFECTS :
- Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - proteinuria Endocrine - hyperglycemia
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 39,355,1976
Urea, (diphenylmethyl)- (8CI)(9CI)合成路线
Urea, (diphenylmethyl)- (8CI)(9CI)上下游产品
Urea, (diphenylmethyl)- (8CI)(9CI)上游产品
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