6-(4-氟苯基)-5-(4-吡啶基)-2,3-二氢咪唑并[2,1-B]-噻唑
用途
名称
[ CAS 号 ]:
72873-74-6
[ 中文名 ]:
6-(4-氟苯基)-5-(4-吡啶基)-2,3-二氢咪唑并[2,1-b]-噻唑
[ 英文名 ]:
SKF 86002
[英文别名 ]:
- MFCD00869367
- SKF-86002
生物活性
[ 描述 ]:
[ 相关类别 ]:
[参考文献]
[相关活性小分子]
物理化学性质
[ 密度 ]:
1.4±0.1 g/cm3
[ 沸点 ]:
476.1±55.0 °C at 760 mmHg
[ 熔点 ]:
189-190ºC(lit.)
[ 分子式 ]:
C16H12FN3S
[ 分子量 ]:
297.350
[ 闪点 ]:
241.7±31.5 °C
[ 精确质量 ]:
297.073608
[ PSA ]:
56.01000
[ LogP ]:
1.90
[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C
[ 折射率 ]:
1.713
[ 储存条件 ]:
2-8℃
安全信息
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves
[ 危害码 (欧洲) ]:
Xi: Irritant;
[ 风险声明 (欧洲) ]:
36/37/38
[ 安全声明 (欧洲) ]:
26-36
[ 危险品运输编码 ]:
NONH for all modes of transport
[ 海关编码 ]:
2934100090
合成路线
上下游产品
上游产品
下游产品
海关
[ 海关编码 ]: 2934100090
[ 中文概述 ]:
2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
文献
Curr. Top. Med. Chem 5(10) , 953-65, (2005)
In the late 1970s and the early 1980s the initial p38 chemotype, the triaryl imidazoles, was discovered as an off-target effect during the development of cyclooxygenase and 5-lipoxygenase inhibitors l...
Activation of p38MAPK contributes to expanded polyglutamine-induced cytotoxicity.PLoS ONE 3(5) , e2130, (2008)
The signaling pathways that may modulate the pathogenesis of diseases induced by expanded polyglutamine proteins are not well understood.Herein we demonstrate that expanded polyglutamine protein cytot...
Differential activation of the c-Jun N-terminal kinase pathway in arsenite-induced apoptosis and sensitization of chemically resistant compared to susceptible B-lymphoma cell lines.Toxicol. Sci. 68(1) , 82-92, (2002)
Various forms of inorganic arsenic are significant environmental contaminants that have multiple effects on cells, including the induction of apoptotic cell death. Induction of apoptosis in lymphoid c...
推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
产品详情:6-(4-氟苯基)-5-(4-吡啶基)-2,3-二氢咪唑并[2,1-b]-噻唑
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥1496.0/10mg
¥3276.0/25mg
¥446.0/1mg
¥5966.0/50mg
联系人:刘佳
产品详情:6-(4-氟苯基)-5-(4-吡啶基)-2,3-二氢咪唑并[2,1-b]-噻唑
公司名:上海源溪生物科技有限公司
区域:上海市浦东新区
价格:
¥需询单/1g
联系人:赖经理
产品详情:SKF-86002
公司名:上海脉铂医药科技有限公司
区域:上海市嘉定区
价格:
¥1605.0/5mg
¥5880.0/25mg
¥436.0/1mg
¥需询单/1mg
联系人:李先生
产品详情:SKF 86002
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥1036.0/5mg
¥需询单/1g
¥需询单/1g
¥需询单/1g
联系人:阿拉丁
产品详情:SKF 86002
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相关化合物
CAS号[72873-74-6]化源网提供[6-(4-氟苯基)-5-(4-吡啶基)-2,3-二氢咪唑并[2,1-B]-噻唑]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版:6-(4-氟苯基)-5-(4-吡啶基)-2,3-二氢咪唑并[2,1-B]-噻唑
标题:72873-74-6_CAS号:72873-74-6_6-(4-氟苯基)-5-(4-吡啶基)-2,3-二氢咪唑并[2,1-B]-噻唑 - 化源网 地址:https://www.chemsrc.com/amp/cas/72873-74-6_671740.html