8-巯基辛酸

8-巯基辛酸 (MOA) 在纳米粒子表面形成自组装单层 (SAM)。MOA 由巯基和羧基组成，有助于不同纳米颗粒的表面处理。MOA 是一种用于石英晶体微天平 (QCMB) 测量的金电极表面修饰 SAM。可作为单层细胞，促进细胞摄取过量铁的金电极上铁蛋白的吸收。也可用于近红外辐射下巨噬细胞光热疗法一氧化氮纳米金 (NO-AuNPs) 的制备。

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
302.0±25.0 °C at 760 mmHg

[ 分子式 ]:
C₈H₁₆O₂S

[ 分子量 ]:
176.276

[ 闪点 ]:
136.4±23.2 °C

[ 精确质量 ]:
176.087097

[ PSA ]:
76.10000

[ LogP ]:
2.33

[ 外观性状 ]:
无色液体

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.486

[ 储存条件 ]:
20°C

详细MSDS(安全技术说明书)

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26

[ 危险品运输编码 ]:
UN 3334

详细合成路线

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Bioorg. Chem. 61 , 36-44, (2015)

Twenty five 4, 6-dichlorobenzimidazole derivatives (1-25) have been synthesized and evaluated against β-glucuronidase inhibitory activity. The compounds which actively inhibit β-glucuronidase activity...

Spastin binds to lipid droplets and affects lipid metabolism.

PLoS Genet. 11 , e1005149, (2015)

Mutations in SPAST, encoding spastin, are the most common cause of autosomal dominant hereditary spastic paraplegia (HSP). HSP is characterized by weakness and spasticity of the lower limbs, owing to ...

Characterization of Lipoyl Synthase from Mycobacterium tuberculosis.

Biochemistry 55 , 1372-83, (2016)

The prevalence of multiple and extensively drug-resistant strains of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, is on the rise, necessitating the identification of new targ...

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