氯化铈,无水

氯化铈,无水用途

【用途一】
用作生产金属铈和其他铈化合物的原料
【用途二】
用作石油催化剂、铈盐原料，也用于制金属铈等。当把氯化铈添加到氰基羟醛（nitrile aldol ）反应时，非对称异构体选择性增强，提高了β-羟基氰（β-hydroxynitriles）的收率。

氯化铈,无水名称

[ CAS 号 ]:
7790-86-5

[ 中文名 ]:
三氯化铈

[ 英文名 ]:
cerium(iii) chloride

[中文别名 ]:

[英文别名 ]:

CeCl3
cerium(iii) chloride
MFCD00010929
CERIUM II CHLORIDE
CEROUS CHLORIDE
Cerium(III)chloride
ceriumtrichloride
Cerium(3+) trichloride
cerium chloride
EINECS 232-227-8

氯化铈,无水物理化学性质

[ 密度 ]:
3.97 g/mL at 25 °C(lit.)

[ 沸点 ]:
1727 °C

[ 熔点 ]:
848 °C(lit.)

[ 分子式 ]:
CeCl₃

[ 分子量 ]:
246.475

[ 闪点 ]:
1727°C

[ 精确质量 ]:
244.811996

[ 外观性状 ]:
白色至灰色粉末

[ 储存条件 ]:
库房低温通风干燥

[ 稳定性 ]:
Stable. Hygroscopic. Incompatible with strong acids, strong oxidizing agents.

氯化铈,无水MSDS

氯化铈,无水毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FK5075000

CHEMICAL NAME :: Cerium chloride

CAS REGISTRY NUMBER :: 7790-86-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: Ce-Cl3

MOLECULAR WEIGHT :: 246.47

WISWESSER LINE NOTATION :: CE G3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2111 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - excitement Lungs, Thorax, or Respiration - other changes

REFERENCE :: AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 100,230,1923

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6262 ug/kg

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), diffuse

REFERENCE :: APYPAY Acta Physiologica Polonica. (Karger-Libri, POB CH-4009, Warszawa, Switzerland) V.1-41, 1950-90. Volume(issue)/page/year: 32,205,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5277 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 97849 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 256,1043,1963

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 188,465,1938

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1289,1935

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 104 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - anorexia (human) Behavioral - muscle weakness

REFERENCE :: AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 15,9,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 211 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975 *** REVIEWS *** TOXICOLOGY REVIEW JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 54,663,1965

氯化铈,无水安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
FK5075000

[ 海关编码 ]:
2846109090

氯化铈,无水合成路线

氯化铈,无水上下游产品

氯化铈,无水上游产品

氯化铈,无水下游产品

氯化铈,无水制备

1.稀土铵复盐法以稀土硫酸铵复盐为原料，经氢氧化钠转化为氢氧化稀土，再用空气氧化为四价铈，经稀盐酸浸出，将铈富集，再经溶解、萃取、结晶，制得氯化铈。

2.含水氯化物装在硬质玻璃管中的石英舟里，用减压装置(维持水银柱高25cm)以1cm3/s的速度通入纯净、干燥的HCl气体，在电炉内70℃温度下维持3h，然后逐步升温到160℃，维持1～2h，再慢慢升温到250℃，趁热打开炉子，转移石英管到保干器(浓硫酸做干燥剂)里面，冷却，然后将产物转移到热的、干燥的试剂瓶，迅速密封即可。

3.按化学计量关系称取反应物，反应物装在悬于电炉中的石英管(d=13～25mm,l=7～25cm)中，选择的电炉应能使样品管各个部位的温度尽可能一致。反应管入口与蒸馏烧瓶的侧口相连(蒸馏烧瓶连有聚四氟乙烯管子)，出口与冷凝接收器(连有聚乙烯管子)相连，每做一次实验后聚乙烯管都需要更换，而聚四氟乙烯管不会受反应的影响(装置如图所示)。

以0.22～0.27g/(min·cm)的速度从样品管滴加CCl4到蒸馏烧瓶中。可用蒸馏烧瓶上的聚四氟乙烯管上的螺旋夹子调整CCl4的流速。用电热罩维持蒸馏烧瓶的温度为100℃，而使用电热带维持预热部分(连接蒸馏烧瓶与反应管的侧管部分)的温度在120℃。

按下列要求控制反应炉温度：500℃ 6h，550℃ 15h，600～650℃ 8h。

反应完成后，通过惰性气体入口充入Ar或者其他惰性气体。断开反应管，配上活塞，连接真空系统，抽真空，密封保存。

氯化铈,无水海关

[ 海关编码 ]: 2846109090

氯化铈,无水文献

Scalable synthesis of the VEGF-R2 kinase inhibitor JNJ-17029259 using ultrasound-mediated addition of MeLi-CeCl3 to a nitrile.

J. Org. Chem. 73(3) , 1121-3, (2008)

The preparation of the selective VEGF-R2 kinase inhibitor 10 (JNJ-17029259) is described in which the key precursor, 4-(5-isoxazolyl)benzonitrile, undergoes clean transformation to the corresponding c...

Difference of EGCg adhesion on cell surface between Staphylococcus aureus and Escherichia coli visualized by electron microscopy after novel indirect staining with cerium chloride

J. Microbiol. Methods 86(1) , 97-103, (2011)

We developed a novel method using indirect staining with cerium chloride for visualization of the catechin derivative epigallocatechin gallate (EGCg) on the surface of particles, i.e., polystyrene bea...

Antioxidative role of cerium against the toxicity of lead in the liver of silver crucian carp.

Fish Physiol. Biochem. 36(3) , 367-76, (2010)

The antioxidative role of cerium was investigated in the liver of silver crucian carp injected with lead. The fish were intraperitoneally injected with 10, 20, or 30 mg/kg wet weight PbCl(2). After a ...

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