1,2-二溴丙烷
1,2-二溴丙烷用途
用作有机合成中间体
【用途二】
用于有机合成,也用作溶剂
【用途三】
用作有机合成原料、化学试剂及溶剂。
1,2-二溴丙烷名称
[ CAS 号 ]:
78-75-1
[ 中文名 ]:
1,2-二溴丙烷
[ 英文名 ]:
UNII:FGB8O5N903
[中文别名 ]:
[英文别名 ]:
- 1,2-dibromo-propan
- 1,2-dibromoprpane
- Propane, 1,2-dibromo-
- 1,2-Dobromopropane
- Propylene dibromide
- 2-Bromopropionyl bromide
- 1,2-Dibrompropan
- 1,2-Dibromopropane
- CH2BrCHBrCH3
- 2,3-dibromopropane
1,2-二溴丙烷物理化学性质
[ 密度 ]:
1.9±0.1 g/cm3
[ 沸点 ]:
140.4±8.0 °C at 760 mmHg
[ 熔点 ]:
-55 °C
[ 分子式 ]:
C3H6Br2
[ 分子量 ]:
201.888
[ 闪点 ]:
21.9±17.7 °C
[ 精确质量 ]:
199.883606
[ LogP ]:
2.43
[ 外观性状 ]:
透明液体
[ 蒸汽压 ]:
7.7±0.2 mmHg at 25°C
[ 折射率 ]:
1.511
[ 储存条件 ]:
库房通风低温干燥,与食品、氧化剂、酸类分开储运
[ 稳定性 ]:
Stable. Flammable. Incompatible with strong oxidizing agents, strong bases, magnesium.
[ 水溶解性 ]:
slightly soluble
1,2-二溴丙烷MSDS
1,2-二溴丙烷毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX8574000
- CHEMICAL NAME :
- Propane, 1,2-dibromo-
- CAS REGISTRY NUMBER :
- 78-75-1
- BEILSTEIN REFERENCE NO. :
- 1718884
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C3-H6-Br2
- MOLECULAR WEIGHT :
- 201.91
- WISWESSER LINE NOTATION :
- EY1&1E
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 741 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12 gm/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 676 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 75716 ug/kg
- REFERENCE :
- CRTOEC Chemical Research in Toxicology. (American Chemical Soc., Distribution Office Dept. 223, POB 57/36, West End Station, Washington, DC 20037) V.1- 1988- Volume(issue)/page/year: 4,528,1991 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6607 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
1,2-二溴丙烷安全信息
[ 符号 ]:
GHS02, GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H226-H302 + H332
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xn:Harmful;
[ 风险声明 (欧洲) ]:
R10;R20/21/22;R36/37/38
[ 安全声明 (欧洲) ]:
S23-S24/25-S36/37/39-S26-S16
[ 危险品运输编码 ]:
UN 1993 3/PG 3
[ WGK德国 ]:
3
[ RTECS号 ]:
TX8574000
[ 包装等级 ]:
III
[ 危险类别 ]:
3
[ 海关编码 ]:
29033036
1,2-二溴丙烷合成路线
1,2-二溴丙烷上下游产品
1,2-二溴丙烷上游产品
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1,2-二溴丙烷制备
1,2-二溴丙烷海关
[ 海关编码 ]: 29033036
1,2-二溴丙烷文献
J. Chromatogr. A. 1407 , 208-15, (2015)
Haloketones (HKs) are unregulated volatile disinfection by-products that show some potential risk even at low concentrations. While EPA Method 551.1 involves conventional liquid-liquid extraction and ...
Simultaneous quantification of trihalomethanes and haloacetic acids in cheese by on-line static headspace gas chromatography-mass spectrometry.J. Chromatogr. A. 1408 , 22-9, (2015)
Trihalomethanes (THMs) and haloacetic acids (HAAs) are the two most prevalent classes of disinfection by-products (DBPs) that are present in treated water. Four THMs and six HAAs are regulated by seve...
[Research concerning rutin semisynthetic derivatives. Synthesis, physico-chemical and microbiological characterisation of some new rutin-isoniazid derivatives].Rev. Med. Chir. Soc. Med. Nat. Iasi. 112(1) , 249-52, (2008)
Isoniazid is one of the most used antituberculosis drugs, but its toxicity is high. In this study, four derivatives of rutin and isoniazid were prepared and their antibacterial and antimycotic activit...
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