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8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤

8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤用途

MMPX is a selective inhibitor of Ca2±calmodulin-dependent phosphodiesterase I (PDE1).

8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤名称

[ CAS 号 ]:
78033-08-6

[ 中文名 ]:
8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤

[ 英文名 ]:
MMPX

[英文别名 ]:

Tocris-0552
8-Methoxymethyl-IBMX
8-methoxymethyl-3-isobutyl-1-methylxanthine
3-isobutyl-8-methoxymethyl-1-methylxanthine
MFCD00211081
Lopac-M-2547

8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤物理化学性质

[ 密度 ]:
1.249g/cm3

[ 沸点 ]:
476.4ºC at 760 mmHg

[ 熔点 ]:
189-190ºC

[ 分子式 ]:
C₁₂H₁₈N₄O₃

[ 分子量 ]:
266.29600

[ 闪点 ]:
241.9ºC

[ 精确质量 ]:
266.13800

[ PSA ]:
81.91000

[ LogP ]:
0.22570

[ 折射率 ]:
1.554

[ 储存条件 ]:
2-8°C，密封，干燥

8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933990090

8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤合成路线

详细合成路线

8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤上下游产品

8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤上游产品

8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤下游产品

8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

8-甲氧基甲基-3-异丁酰-1-甲基黄嘌呤文献

In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease.

Nat. Commun. 6 , 6965, (2015)

3',5'-cyclic adenosine monophosphate (cAMP) is an ubiquitous second messenger that regulates physiological functions by acting in distinct subcellular microdomains. Although several targeted cAMP bios...

Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta.

Biochem. Pharmacol. 38 , 3331, (1989)

In this study three forms of cyclic nucleotide phosphodiesterase (PDE) isolated from rabbit aorta were pharmacologically characterized, and the consequence of selective inhibition of calmodulin-stimul...

Methylxanthine inhibitors of phosphodiesterases.

Meth. Enzymol. 159 , 489, (1988)

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