1, 2-Didemethylcolchicine

1, 2-Didemethylcolchicine名称

[ CAS 号 ]:
78231-83-1

[ 英文名 ]:
1, 2-Didemethylcolchicine

[英文别名 ]:

1,2-Didemethylcolchicine
1,2-O-didemethylcolchicine

1, 2-Didemethylcolchicine物理化学性质

[ 密度 ]:
1.38g/cm3

[ 沸点 ]:
783.5ºC at 760 mmHg

[ 分子式 ]:
C₂₀H₂₁NO₆

[ 分子量 ]:
371.38400

[ 闪点 ]:
427.6ºC

[ 精确质量 ]:
371.13700

[ PSA ]:
105.09000

[ LogP ]:
2.65650

[ 折射率 ]:
1.642

1, 2-Didemethylcolchicine毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AC8585500

CHEMICAL NAME :: Acetamide, N-(5,6,7,9-tetrahydro-1,2-dihydroxy-3,10-dimethoxy-9- oxobenzo(a)heptalen-7 -yl)-, (S)-

CAS REGISTRY NUMBER :: 78231-83-1

LAST UPDATED :: 198912

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H21-N-O6

MOLECULAR WEIGHT :: 371.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 167 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1365,1983

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