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2-羟基异丁酸乙酯

2-羟基异丁酸乙酯用途

用于有机合成。乙酸纤维、硝化纤维的溶剂。主要用作涂料用溶剂，由于挥发速度慢，加到纤维素酯的涂料中使涂膜表面美观，涂刷性能好。

2-羟基异丁酸乙酯名称

[ CAS 号 ]:
80-55-7

[ 中文名 ]:
2-羟基异丁酸乙酯

[ 英文名 ]:
Ethyl α-hydroxyisobutyrate

[中文别名 ]:

[英文别名 ]:

Ethyl α-hydroxyisobutyrate
Ethyl 2-hydroxy-2-methylpropanoate
EINECS 201-290-3
Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester
MFCD00004458

2-羟基异丁酸乙酯物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
152.1±8.0 °C at 760 mmHg

[ 分子式 ]:
C₆H₁₂O₃

[ 分子量 ]:
132.158

[ 闪点 ]:
44.4±0.0 °C

[ 精确质量 ]:
132.078644

[ PSA ]:
46.53000

[ LogP ]:
0.16

[ 外观性状 ]:
透明无色液体

[ 蒸汽压 ]:
1.3±0.6 mmHg at 25°C

[ 折射率 ]:
1.428

[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开存放

2-羟基异丁酸乙酯MSDS

2-羟基异丁酸乙酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OD5672000

CHEMICAL NAME :: Lactic acid, 2-methyl-, ethyl ester

CAS REGISTRY NUMBER :: 80-55-7

BEILSTEIN REFERENCE NO. :: 0878308

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H12-O3

MOLECULAR WEIGHT :: 132.18

WISWESSER LINE NOTATION :: QX1&1&VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 76,189,1942 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7053 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 919 (estimated) No. of Female Employees: 306 (estimated)

2-羟基异丁酸乙酯安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H226-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R10;R36/38

[ 安全声明 (欧洲) ]:
S26-S36-S16

[ 危险品运输编码 ]:
UN 3272 3/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
OD5672000

[ 包装等级 ]:
III

[ 危险类别 ]:
3

[ 海关编码 ]:
29181980

2-羟基异丁酸乙酯合成路线

2-羟基异丁酸乙酯上下游产品

2-羟基异丁酸乙酯上游产品

2-羟基异丁酸乙酯下游产品

2-羟基异丁酸乙酯制备

精制方法：含有游离的酸、醇和水等杂质。精制时用无水碳酸钾或硫酸钠干燥后蒸馏。

2-羟基异丁酸乙酯海关

[ 海关编码 ]: 2918199090

[ 中文概述 ]:
HS: 2918199090. 其他含醇基但不含其他含氧基羧酸（包括其酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%