<生产厂家价格>

凡士林

凡士林用途

消泡剂；润滑剂；脱膜剂；保护涂层。

广泛的用作发蜡、发乳、冷霜、润肤霜、防裂霜、乳液、唇膏等化妆品的基质原料，也是含药物化妆品中各种软膏制品的基质原料。

凡士林名称

[ CAS 号 ]:
8009-03-8

[ 中文名 ]:
凡士林

[ 英文名 ]:
Petrolatum

[英文别名 ]:

MFCD00147839
EINECS 232-373-2

凡士林生物活性

[ 描述 ]:

凡士林(白色)是许多药物的软膏载体,因为它对皮肤的刺激性很低。凡士林(白色)可用作赋形剂,如软膏基质、润滑剂、粘合剂、增粘剂、赋形剂等。药用辅料,或称药用辅料,是指除药物成分外,在制药过程中使用的其他化学物质。药用辅料一般是指药物制剂中的非活性成分,可以提高药物制剂的稳定性、溶解性和加工性。药用辅料也会影响联合给药药物的吸收、分布、代谢和消除(ADME)过程[1][2]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Ishii H, et al. Why does a hydrophilic drug permeate skin, although it is not soluble in white petrolatum?[J]. Drug development and industrial pharmacy, 2009, 35(11): 1356-1363.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

凡士林物理化学性质

[ 密度 ]:
0.84

[ 沸点 ]:
322 °C

[ 熔点 ]:
70-80 °C ((ASTM D 127))

[ 分子式 ]:
C₈₆H₁₄₂

[ 闪点 ]:
198 °C

[ 外观性状 ]:
extra-low viscosity | white

[ 折射率 ]:
n20/D 1.45

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

凡士林安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
T

[ 风险声明 (欧洲) ]:
R45

[ 安全声明 (欧洲) ]:
S53;S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
RV0350000

凡士林制备

主要采用精制法。以石油高黏度馏分为原料，先进行脱蜡，再掺和中等黏度润滑油，然后加入发烟硫酸和活性白土脱臭、脱色而得。也可采用加氢方法进一步精制。

凡士林文献

Comparative study of the efficacy and tolerability of a unique topical scar product vs white petrolatum following shave biopsies.

Journal. of. Drugs in. Dermatology. 12(1) , 86-90, (2013)

An excess of 70 million cutaneous surgical procedures are conducted annually in the United States that may result in scarring. Skin scars are a normal outcome of the tissue repair process. However, in...

Contact allergy to air-exposed geraniol: clinical observations and report of 14 cases.

Contact Dermatitis 67(1) , 20-7, (2012)

The fragrance terpene geraniol forms sensitizing compounds via autoxidation and skin metabolism. Geranial and neral, the two isomers of citral, are the major haptens formed in both of these activation...

Comparative evaluation of antimicrobial efficacy of various root canal filling materials along with aloevera used in primary teeth: a microbiological study.

J. Clin. Pediatr. Dent. 37(3) , 257-62, (2013)

this study was conducted to evaluate the antimicrobial effectiveness of 6 root canal filling materials and a negative control agent against 18 strains of bacteria isolated from infected root canals of...

更多文献

凡士林