(-)-MDO-NPA HCl

(-)-MDO-NPA HCl用途

(-)-MDO-NPA HCl is an orally effective long-acting agent active at central dopamine receptors, and analogous aporphines.

(-)-MDO-NPA HCl名称

[ CAS 号 ]:
81264-57-5

[ 英文名 ]:
(-)-MDO-NPA HCl

[英文别名 ]:

(R)-MDO-NPA
(S)-Propane-1,2-diamine dihydrochloride
R-(-)-1,2-propanediamine dihydrochloride
(S)-1,2-diaminopropane
(S)-diaminopropane dihydrochloride
R(-)-10,11-Methylenedioxy-N-(n-propyl)noraporphine
(S)-1,2-propanediamine*2HCl
(S)-1,2-Diaminopropane 2HCl
S-(-)-1,2-diaminopropane dihydrochloride
(S)-1,2-Propanediamine dihydrochloride

(-)-MDO-NPA HCl物理化学性质

[ 密度 ]:
1.209g/cm3

[ 沸点 ]:
456ºC at 760 mmHg

[ 熔点 ]:
250-252ºC

[ 分子式 ]:
C₂₀H₂₁NO₂

[ 分子量 ]:
307.38600

[ 闪点 ]:
165.2ºC

[ 精确质量 ]:
307.15700

[ PSA ]:
21.70000

[ LogP ]:
3.88550

[ 折射率 ]:
1.622

(-)-MDO-NPA HCl安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

(-)-MDO-NPA HCl合成路线

详细合成路线

(-)-MDO-NPA HCl上下游产品

(-)-MDO-NPA HCl上游产品

(-)-MDO-NPA HCl下游产品

(-)-MDO-NPA HCl文献

Behavioral effects of (-)10,11-methylenedioxy-N-n-propylnoraporphine, an orally effective long-acting agent active at central dopamine receptors, and analogous aporphines.

Neuropharmacology 21(10) , 953-61, (1982)

Substituted and unsubstituted 10,11-methylenedioxy derivatives of apomorphine (APO) or its N-propyl congener (NPA) were synthesized and evaluated for their ability to alter motor activity or to induce...

Dopaminergic stimulation of oxytocin concentrations in the plasma of male and female monkeys by apomorphine and a D2 receptor agonist.

J. Clin. Endocrinol. Metab. 75(3) , 855-60, (1992)

Administration of the dopamine receptor agonist apomorphine causes a dose-dependent increase in plasma oxytocin concentrations and dose-specific behavioral changes in rodents. To investigate whether d...

Tissue levels of N-n-propylnorapomorphine after treatment with (-)10,11-methylenedioxy-N-n-propylnoraporphine, an orally long-acting prodrug active at central dopamine receptors.

Neuropharmacology 21(12) , 1311-6, (1982)

High performance liquid chromatography with electrochemical detection was used to assay N-n-propylnorapomorphine (NPA) and other aporphines. Pretreatment of rats with (-)10,11-methylenedioxy-N-n-propy...

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