N6-甲基腺苷 5'-单磷酸酯钠盐

N6-甲基腺苷 5'-单磷酸酯钠盐用途

N6-Methyladenosine 5'-monophosphate disodium salt 是糖原磷酸化酶 b 的激活剂,Ka 值为22 µM。N6-Methyladenosine 5'-monophosphate disodium salt 也是腺苷酸激酶II 的抑制剂。

N6-甲基腺苷 5'-单磷酸酯钠盐名称

[ CAS 号 ]:
81921-35-9

[ 中文名 ]:
N6-甲基腺苷 5'-单磷酸酯钠盐

[ 英文名 ]:
N6-Methyladenosine 5'-Monophosphate Sodium Salt

[英文别名 ]:

N6-Methyladenosine-5'-monophosphate sodium salt
N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT

N6-甲基腺苷 5'-单磷酸酯钠盐生物活性

[ 描述 ]:

N6-Methyladenosine 5'-monophosphate disodium salt 是糖原磷酸化酶 b 的激活剂,Ka 值为22 µM。N6-Methyladenosine 5'-monophosphate disodium salt 也是腺苷酸激酶II 的抑制剂。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[ 靶点 ]

Ki: 22 Glycogen phosphorylase b[1]. Adenylate kinase II[2].

[参考文献]

[1]. Groner Y, et al. 5'-Capping structures of Artemia salina mRNA and the translational inhibition by cap analogs. Eur J Biochem. 1976 Dec;71(1):281-93.

[2]. Hai TT, et al. Species- or isozyme-specific enzyme inhibitors. 9. Selective effects in inhibitions of rat pyruvate kinase isozymes by adenosine 5'-diphosphate derivatives. J Med Chem. 1982 Oct;25(10):1184-8.

N6-甲基腺苷 5'-单磷酸酯钠盐物理化学性质

[ 分子式 ]:
C₁₁H₁₄N₅Na₂O₇P

[ 分子量 ]:
405.21

[ 精确质量 ]:
384.06900

[ PSA ]:
181.89000

[ 储存条件 ]:
-20°C，密闭，干燥

N6-甲基腺苷 5'-单磷酸酯钠盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

N6-甲基腺苷 5'-单磷酸酯钠盐文献

AMP analogs: their function in the activation of glycogen phosphorylase b.

Eur. J. Biochem. 65 , 553, (1976)

A series of AMP analogs has been selected in order to better understand the structural requirements (a) for the efficient binding of the activator molecule at the correct site on phosphorylase b from ...

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