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土荆皮甲酸

土荆皮甲酸用途

Pseudolaric Acid A 是一种从 Pseudolarix kaempferi 分离的二萜酸,具有抗真菌,细胞毒性,抗受精活性。

土荆皮甲酸名称

[ CAS 号 ]:
82508-32-5

[ 中文名 ]:
土槿皮甲酸

[ 英文名 ]:
Pseudolaric Acid A

[中文别名 ]:

[英文别名 ]:

土荆皮甲酸生物活性

土荆皮甲酸物理化学性质

[ 密度 ]:
1.23

[ 沸点 ]:
571.5±50.0 °C at 760 mmHg

[ 熔点 ]:
206-207 ºC

[ 分子式 ]:
C22H28O6

[ 分子量 ]:
388.454

[ 闪点 ]:
196.6±23.6 °C

[ 精确质量 ]:
388.188599

[ PSA ]:
89.90000

[ LogP ]:
3.49

[ 蒸汽压 ]:
0.0±3.4 mmHg at 25°C

[ 折射率 ]:
1.563

[ 储存条件 ]:
2-8C

土荆皮甲酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RZ2473800
CHEMICAL NAME :
2,4-Pentadienoic acid, 5-(4a-(acetyloxyl)-3,4,4a,5,6,9-hexahydro-3,7-dimethy l-1-oxo- 1H-4,9a-ethanocyclohepta(c)pyran-3-yl)-2-methyl-, (3-alpha(2E,4E),4-alpha,9a-alpha)-(-)- (9CI)
CAS REGISTRY NUMBER :
82508-32-5
LAST UPDATED :
199309
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C22-H28-O6
MOLECULAR WEIGHT :
388.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
219 mg/kg
TOXIC EFFECTS :
Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea
REFERENCE :
CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 9,445,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
397 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness
REFERENCE :
CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 9,445,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
486 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness
REFERENCE :
CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 9,445,1988 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
24600 ug/kg
SEX/DURATION :
female 7-9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
REFERENCE :
CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 9,445,1988
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
200 mg/kg
SEX/DURATION :
female 7-11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 9,445,1988

推荐生产厂家/供应商:

公司名:上海化源世纪贸易有限公司

区域:上海市普陀区

价格:

联系人:徐经理

产品详情:土荆皮甲酸


公司名:云南西力生物技术股份有限公司

区域:昆明市盘龙区

价格:
¥需询单/5mg

联系人:郑雪平

产品详情:土槿皮甲酸


公司名:上海吉至生化科技有限公司

区域:上海市奉贤区

价格:
¥1178.0/10mg

联系人:刘佳

产品详情:土荆皮甲酸


公司名:上海脉铂医药科技有限公司

区域:上海市嘉定区

价格:
¥1989.0/20mg ¥需询单/1g ¥需询单/1g ¥需询单/1g

联系人:李先生

产品详情:Pseudolaric acid A


公司名:上海创赛科技有限公司

区域:上海市嘉定区

价格:
¥2052.0/10mg ¥1960.0/20mg

联系人:夏言

产品详情:[Perfemiker]土荆皮甲酸,≥98%(HPLC)


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