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盐酸莫昔普利

盐酸莫昔普利用途

Moexipril盐酸盐是口服活性的不含巯基的血管紧张素转化酶抑制剂,可作用于高血压和充血性心力衰竭。

盐酸莫昔普利名称

[ CAS 号 ]:
82586-52-5

[ 中文名 ]:
盐酸莫昔普利

[ 英文名 ]:
Moexipril HCl

[中文别名 ]:

莫西普利盐酸盐

[英文别名 ]:

Uniretic
Univasc
SPM 925
Moexipril HCl
Moexipril HCL
MOEXIPRIL HYDROCHLORIDE
CI-925
UNII-Q1UMG3UH45
Moexipril (hydrochloride)

盐酸莫昔普利生物活性

[ 描述 ]:

Moexipril盐酸盐是口服活性的不含巯基的血管紧张素转化酶抑制剂,可作用于高血压和充血性心力衰竭。

[ 相关类别 ]:

信号通路 >> 代谢酶/蛋白酶 >> 血管紧张素转换酶(ACE)

研究领域 >> 心血管疾病

[参考文献]

[1]. Chrysant, S.G. and G.S. Chrysant, Pharmacological and clinical profile of moexipril: a concise review. J Clin Pharmacol, 2004. 44(8): p. 827-36.

[2]. Edling, O., et al., Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril. J Pharmacol Exp Ther, 1995. 275(2): p. 854-63.

[3]. Song, J.C. and C.M. White, Clinical pharmacokinetics and selective pharmacodynamics of new angiotensin converting enzyme inhibitors: an update. Clin Pharmacokinet, 2002. 41(3): p. 207-24.

[相关活性小分子]

盐酸莫昔普利物理化学性质

[ 沸点 ]:
709.3ºC at 760 mmHg

[ 熔点 ]:
141-161ºC

[ 分子式 ]:
C₂₇H₃₅ClN₂O₇

[ 分子量 ]:
535.03

[ 闪点 ]:
382.8ºC

[ PSA ]:
114.40000

[ LogP ]:
3.71510

[ 外观性状 ]:
一种细白色至灰白色粉末

[ 储存条件 ]:
2-8°C

盐酸莫昔普利安全信息

[ 符号 ]:

GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H400

[ 警示性声明 ]:
P273

[ 个人防护装备 ]:
Eyeshields;Gloves

[ 危害码 (欧洲) ]:
N:Dangerous for the environment

[ 风险声明 (欧洲) ]:
R50

[ 安全声明 (欧洲) ]:
60

[ 危险品运输编码 ]:
UN 3077

[ RTECS号 ]:
NW7174500

盐酸莫昔普利合成路线

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盐酸莫昔普利文献

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