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1,8-萘磺酸内酯

1,8-萘磺酸内酯用途

用于有机合成。有机合成中间体。

1,8-萘磺酸内酯名称

[ CAS 号 ]:
83-31-8

[ 中文名 ]:
1,8-萘磺酸内酯

[ 英文名 ]:
Naphth(1,8-cd)-1,2-oxathiole, 2,2-dioxide

[中文别名 ]:

1,8-萘砜

[英文别名 ]:

1,8-NAPHTHALENESULTONE
Naphth[1,8-cd]-1,2-oxathiole, 2,2-dioxide
MFCD00005937
Naphth(1,8-cd)-1,2-oxathiole, 2,2-dioxide
8-Naphthosultone
Naphtho[1,8-cd][1,2]oxathiole 2,2-dioxide
naphthosultone
1-naphthol-8-sulfonic acid sultone
naphthalene-1,8-sultone
1,8-Naphthosulftone

1,8-萘磺酸内酯物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
419.5±18.0 °C at 760 mmHg

[ 熔点 ]:
154-157 °C (dec.)(lit.)

[ 分子式 ]:
C₁₀H₆O₃S

[ 分子量 ]:
206.218

[ 闪点 ]:
207.5±21.2 °C

[ 精确质量 ]:
206.003769

[ PSA ]:
51.75000

[ LogP ]:
2.40

[ 外观性状 ]:
淡黄色晶体

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.729

[ 储存条件 ]:
室温

1,8-萘磺酸内酯MSDS

1,8-萘磺酸内酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R38

[ 安全声明 (欧洲) ]:
S22-S28

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2934991000

1,8-萘磺酸内酯合成路线

1,8-萘磺酸内酯上下游产品

1,8-萘磺酸内酯上游产品

1,8-萘磺酸内酯下游产品

1,8-萘磺酸内酯海关

[ 海关编码 ]: 2934991000

[ 中文概述 ]:
2934991000. 磺内酯及磺内酰胺. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934991000. sultones and sultams. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

1,8-萘磺酸内酯文献

Studies of the chemical selectivity of hapten, reactivity, and skin sensitization potency. 1. Synthesis and studies on the reactivity toward model nucleophiles of the (13)C-labeled skin sensitizers hex-1-ene- and hexane-1,3-sultones.

Chem. Res. Toxicol. 14(1) , 110-7, (2001)

The potent skin sensitizers hex-1-ene- and hexane-1,3-sultone have been synthesized isotopically labeled with (13)C at reactive sites. The reactivity of 2-[(13)C]- and 3-[(13)C]hex-1-ene-1,3-sultones ...

Studies of the chemical selectivity of hapten, reactivity, and skin sensitization potency. 2. nmr studies of the covalent binding of the (13)c-labeled skin sensitizers 2-[13C]- and 3-[13C]hex-1-ene- and 3-[13C]hexane-1,3-sultones to human serum albumin.

Chem. Res. Toxicol. 14(1) , 118-26, (2001)

3-[(13)C]- and 2-[(13)C]hex-1-ene-1,3-sultones (1a and 1b, respectively) and 3-[(13)C]hex-1-ene-1,3-sultone 2a were incubated with human serum albumin in phosphate buffer at pH 8.1. In both cases, the...

4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus.

J. Med. Chem. 52(6) , 1582-91, (2009)

We report the synthesis and antiviral activity of a new family of non-nucleoside antivirals, derived from the 4-keto-1,2-oxathiole-2,2-dioxide (beta-keto-gamma-sultone) heterocyclic system. Several 4-...

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