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鞘磷脂(来自牛脑)

鞘磷脂(来自牛脑)用途

Sphingomyelin是在动物细胞膜中发现的一种鞘脂,并且涉及跨膜信号传导的调节。

鞘磷脂(来自牛脑)名称

[ CAS 号 ]:
85187-10-6

[ 中文名 ]:
鞘磷脂

[ 英文名 ]:
sphingomyelin

[中文别名 ]:

鞘磷酯

[英文别名 ]:

EINECS 286-097-2
N-acylsphingosylphosphocholine
Sphingomyelins
N-acyl-sphing-4-enine-1-phosphocholine
N-acyl-sphingosylphosphorylcholine
N-acyl-sphingosylphosphorylcholines
MFCD00132361
N-acyl-sphingosylphosphocholines

鞘磷脂(来自牛脑)生物活性

[ 描述 ]:

Sphingomyelin是在动物细胞膜中发现的一种鞘脂,并且涉及跨膜信号传导的调节。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Chakraborty M, et al. Sphingomyelin and its role in cellular signaling. Adv Exp Med Biol. 2013;991:1-14.

[相关活性小分子]

鞘磷脂(来自牛脑)物理化学性质

[ 分子式 ]:
C₄₁H₈₄N₂O₆P

[ 分子量 ]:
732.08

[ PSA ]:
144.36000

[ LogP ]:
9.53

[ 外观性状 ]:
powder | white

[ 储存条件 ]:
−20°C

鞘磷脂(来自牛脑)MSDS

详细MSDS(安全技术说明书)

鞘磷脂(来自牛脑)安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

鞘磷脂(来自牛脑)文献

Sphingomyelin depletion impairs anionic phospholipid inward translocation and induces cholesterol efflux.

J. Biol. Chem. 288(52) , 37166-79, (2013)

The phosphatidylserine (PS) floppase activity (outward translocation) of ABCA1 leads to plasma membrane remodeling that plays a role in lipid efflux to apolipoprotein A-I (apoAI) generating nascent hi...

Characterization of freeze-fractured epithelial plasma membranes on nanometer scale with ToF-SIMS.

Anal. Bioanal. Chem , (2014)

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) was used to characterize the freeze-fracturing process of human epithelial PANC-1 and UROtsa cells. For this purpose, phosphatidylcholine, sph...

Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers.

J. Biol. Chem. 265(9) , 4923-8, (1990)

Vascular anticoagulant alpha (VAC alpha, annexin V) is a member of the family of calcium and phospholipid binding proteins, the annexins. The binding properties of VAC alpha to phospholipid bilayers w...

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