(5α,17β)-3-Oxoandrostan-17-yl propionate
名称
[ CAS 号 ]:
855-22-1
[ 英文名 ]:
(5α,17β)-3-Oxoandrostan-17-yl propionate
[英文别名 ]:
- Dihydrotestosterone propionate
- Androstanolone acetate
- Stanolone Acetate
- 17-O-Acetyldihydrotestosterone
物理化学性质
[ 密度 ]:
1.08g/cm3
[ 沸点 ]:
438ºC at 760 mmHg
[ 分子式 ]:
C22H34O3
[ 分子量 ]:
346.50400
[ 闪点 ]:
188ºC
[ 精确质量 ]:
346.25100
[ PSA ]:
43.37000
[ LogP ]:
4.92000
[ 折射率 ]:
1.524
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BV8071500
- CHEMICAL NAME :
- 5-alpha-Androstan-3-one, 17-beta-hydroxy-, propionate
- CAS REGISTRY NUMBER :
- 855-22-1
- BEILSTEIN REFERENCE NO. :
- 2628403
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C22-H34-O3
- MOLECULAR WEIGHT :
- 346.56
- WISWESSER LINE NOTATION :
- L E5 B666 OVTJ A1 E1 FOV2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 50 ug/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 30,55,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 20 mg/kg
- SEX/DURATION :
- female 4 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 20,384,1979
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 3 gm/kg
- SEX/DURATION :
- male 6 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
- REFERENCE :
- JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939- Volume(issue)/page/year: 51,241,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 150 mg/kg
- SEX/DURATION :
- female 28-58 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - delayed effects
- REFERENCE :
- HOBEAO Hormones and Behavior. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 6,139,1975
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- DOSE :
- 208 mg/kg
- SEX/DURATION :
- male 82 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 94,57,1992
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